Introduction: What Do we Know of the Mechanisms of Alcohol Damage
            <i>in vitro</i>
            ?

Pratt, O. E.

doi:10.1002/9780470720868.ch1

Cited by 7 publications

(4 citation statements)

References 21 publications

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“…Cigarettes also contain many other toxic chemicals, including lead that can affect a developing fetus. The teratogenicity of alcohol has been established [38][39][40][41]. This literature shows the importance for outcome of the dose, timing and conditions of exposure, as well as individual sensitivity of both mother and offspring [40].…”

Section: Ijomeh 2015;28(3) 437mentioning

confidence: 99%

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Smoking and alcohol drinking during pregnancy as the risk factors for poor child neurodevelopment – A review of epidemiological studies

Polańska¹,

Jurewicz²,

Hanke³

2015

Int J Occup Med Environ Health

115

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Maternal active and passive smoking and low or moderate alcohol drinking during pregnancy, taking into account the level of exposure and developmental or behavioral outcomes, are recognized as a significant issue from both a clinical and a public health perspective. The article aims at evaluating the impact of prenatal exposure to tobacco smoke constituents and low or moderate alcohol drinking during pregnancy on children neurodevelopment by reviewing the most recently published literature. Relevant studies were identified by searching the Pubmed, Medline and Ebsco literature databases. This review is restricted to 29 human studies published in English in peer reviewed journals since 2006. The studies published recently continued to show some relationship between tobacco smoke exposure, from active and passive maternal smoking during pregnancy, and children's psychomotor development independent of other variables, but this relationship is not straightforward. The association is mostly consistent for measures of academic achievements and behavioral problems which require further attention. The results of the studies on low or moderate exposure to alcohol are not fully conclusive, but some of them suggest that consumption of alcohol during pregnancy may adversely affect children's intelligence quotient (IQ), mental health, memory and verbal or visual performance. As the reviewed studies indicate, maternal lifestyle during pregnancy like alcohol drinking or smoking may affect children neurodevelopment. All effort should be taken to eliminate such exposure to ensure appropriate children's development.

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Section: Ijomeh 2015;28(3) 437mentioning

confidence: 99%

“…Ethanol enhances migration of nerve cells, which is hypothesized to be involved in behavioral difficulties in childhood. It also interferes with the production of neuroendocrine hormones, which may perturb brain growth [41].…”

Section: Ijomeh 2015;28(3) 437mentioning

confidence: 99%

Smoking and alcohol drinking during pregnancy as the risk factors for poor child neurodevelopment – A review of epidemiological studies

Polańska¹,

Jurewicz²,

Hanke³

2015

Int J Occup Med Environ Health

115

View full text Add to dashboard Cite

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“…Ethanol enhances migration of nerve cells, which is hypothesized to be involved in behavioural difficulties in childhood. It also interferes with the production of neuroendocrine hormones, which may perturb brain growth [92]. Six studies examined the association between exposure to alcohol and ADHD and ADHD related symptoms ( Table 5).…”

Section: Alcohol and Adhd Or Adhd Symptomsmentioning

confidence: 99%

Exposure to environmental and lifestyle factors and attention-deficit / hyperactivity disorder in children — A review of epidemiological studies

Polańska¹,

Jurewicz²,

Hanke³

2012

International Journal of Occupational Medicine and Environmental Health

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Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children. Although the mechanisms that lead to the development of ADHD remain unclear, genetic and environmental factors have been implicated. These include heavy metals and chemical exposures, nutritional and lifestyle/psychosocial factors. The aim of this review was to investigate the association between ADHD or ADHD-related symptoms and widespread environmental factors such as phthalates, bisphenol A (BPA), tobacco smoke, polycyclic aromatic hydrocarbons (PAHs), polyfluoroalkyl chemicals (PFCs) and alcohol. Medline, PubMed and Ebsco search was performed to identify the studies which analyze the association of prenatal and postnatal child exposure to environmental toxicants and lifestyle factors and ADHD or ADHD-related symptoms. The review is restricted to human studies published since 2000 in English in peer reviewed journals. Despite much research has been done on the association between environmental risk factors and ADHD or ADHD symptoms, results are not consistent. Most studies in this field, focused on exposure to tobacco smoke, found an association between that exposure and ADHD and ADHD symptoms. On the other hand, the impact of phthalates, BPA, PFCs, PAHs and alcohol is less frequently investigated and does not allow a firm conclusion regarding the association with the outcomes of interest.

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“…On the other hand, alcohol is a known teratogenic substance, strengthening the migration of nerve cells, and is suspected to be involved in behavioral disorders in childhood. Furthermore, it intervenes in the production of neuroendocrine hormones, which can disturb brain development [39]. prenatal alcohol exposure can be a significant risk factor, if there is excessive consumption in pregnancy [43], while the study of Sagiv, K. et al, did not show strong correlation between alcohol consumption in pregnancy and ADHD in childhood [44].…”

Section: Maternal Smoking Drug and Alcohol Use And Stress In Pregnancymentioning

confidence: 99%

Perinatal Factors of Developmental Attention Deficit Hyperactivity Disorder in Children

Antoniou¹,

Rigas²,

Papatrechas³

et al. 2021

JBM

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Background: Attention deficit hyperactivity disorder is a common pediatric neurobehavioral disorder often treated in the primary care setting. It shows a high and chronic level of inattention, impulsivity/hyperactivity and/or both, and can affect more than 2 million school-age children. The researchers are not sure about the exact causes of the disorder, but it seems that apart from genetic factors, perinatal factors seem to dynamically contribute to the development of the disorder. Purpose: The aim of this review was to investigate the perinatal and obstetric factors related to the development of the attention deficit hyperactivity disorder in childhood. Method: An online review of English language studies published from 2002 to 2020, using the Embase, Psy-chINFO, PubMed and Google Scholar databases. From 1100 studies only 17 were included in the review since they met the inclusion criteria. Conclusions: The results of the review showed that apart from heredity and genetic factors, various conditions in pregnancy or the mother's way of life in pregnancy, adverse conditions in labor and infancy can contribute on their own or in combination to the development of the attention deficit hyperactivity disorder in childhood. Obstetric vigilance to detect risk factors in pregnancy in combination with the prevention of obstetric complications is the key in preventing attention deficit hyperactivity disorder.

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Introduction: What Do we Know of the Mechanisms of Alcohol Damage in vitro ?

Cited by 7 publications

References 21 publications

Smoking and alcohol drinking during pregnancy as the risk factors for poor child neurodevelopment – A review of epidemiological studies

Smoking and alcohol drinking during pregnancy as the risk factors for poor child neurodevelopment – A review of epidemiological studies

Exposure to environmental and lifestyle factors and attention-deficit / hyperactivity disorder in children — A review of epidemiological studies

Perinatal Factors of Developmental Attention Deficit Hyperactivity Disorder in Children

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