Introduction to soft tissue fillers

Pearlman, Ross L; McClung, Sally J. W.; Schlesinger, Todd

doi:10.1002/der2.190

Cited by 3 publications

(4 citation statements)

References 15 publications

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“…The preference for HA fillers among both practitioners and patients can be attributed to several factors. First, HA fillers have a unique capacity to attract and retain water molecules, which contributes to their volumizing effect and natural-looking results 18 . The hydrophilic nature of HA allows the filler to integrate seamlessly with the surrounding tissues, creating a smooth and cohesive appearance 4 .…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, the cross-linking technology used in modern HA fillers has greatly improved their longevity and stability compared to earlier generations of fillers 18 . The cross-linking process creates a more robust and viscous gel that can resist degradation and maintain its shape for an extended period 19 .…”

Section: Discussionmentioning

confidence: 99%

“…The cross-linking process creates a more robust and viscous gel that can resist degradation and maintain its shape for an extended period 19 . This advancement has made HA fillers more predictable and cost-effective for patients seeking long-lasting results without the need for frequent touch-ups 18 .…”

Section: Discussionmentioning

confidence: 99%

“…From fine lines and wrinkles to deep folds and volume loss, HA fillers can be used to address multiple signs of aging in a single session 20 . The variety of HA filler formulations with different particle sizes, cross-linking densities, and rheological properties allows practitioners to tailor treatments to the specific needs of each patient and to target different areas of the face with precision 18 .…”

Section: Discussionmentioning

confidence: 99%

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Legal analysis of South Korean cosmetic filler litigations for safer medical practices

Kang,

Hong

2024

Sci Rep

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Cosmetic filler injections have gained popularity in recent years, but the rise in complications has led to an increase in legal disputes. This study analyzes civil court rulings related to cosmetic filler injection lawsuits in South Korea from 2007 to 2023. A retrospective case analysis was performed using a systematic database search, and a mixed-methods approach was employed for data analysis. The study examined 27 cases, revealing a high rate of liability findings against medical practitioners. Skin necrosis and blindness were the most common complications, and intravascular filler injection was recognized as negligence. Violation of informed consent was found in most cases, with mean compensation awards of ￦193,019,107 KRW ($142,831 USD) for first instance cases and ￦81,845,052 KRW ($60,564 USD) for second instance cases. The findings emphasize the importance of practitioner awareness, adherence to precautionary measures, and proactive prevention and management of complications. Collaboration among stakeholders is crucial for developing strategies that prioritize patient safety and minimize legal disputes in the aesthetic medicine industry. This study provides valuable insights for enhancing medical practices and safeguarding patient well-being in the field of cosmetic filler injections.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Legal analysis of South Korean cosmetic filler litigations for safer medical practices

Kang,

Hong

2024

Sci Rep

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Between Beauty and the Law: Analyzing Cosmetic Filler Litigations in South Korea for Safer Medical Practices

Kang,

Hong

2024

Preprint

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Cosmetic filler injections have gained popularity in recent years, but the rise in complications has led to an increase in legal disputes. This study analyzes civil court rulings related to cosmetic filler injection lawsuits in South Korea from 2007 to 2023. A retrospective case analysis was performed using a systematic database search, and a mixed-methods approach was employed for data analysis. The study examined 27 cases, revealing a high success rate for plaintiffs. Skin necrosis and blindness were the most common complications, and intravascular filler injection was recognized as negligence. Violation of informed consent was found in most cases, with mean compensation awards of ￦193,019,107 KRW ($142,831 USD) for first instance cases and ￦81,845,052 KRW ($60,564 USD) for second instance cases. The findings emphasize the importance of practitioner awareness, adherence to precautionary measures, and proactive management of complications. Collaboration among stakeholders is crucial for developing strategies that prioritize patient safety and minimize legal disputes in the aesthetic medicine industry. This study provides valuable insights for enhancing medical practices and safeguarding patient well-being in the field of cosmetic filler injections.

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Biocompatibility Study of Purified and Low-Temperature-Sterilized Injectable Collagen for Soft Tissue Repair: Intramuscular Implantation in Rats

Koo,

Lee,

Grogan

et al. 2024

Gels

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The clinical application of collagen-based biomaterials is expanding rapidly, especially in tissue engineering and cosmetics. While oral supplements and injectable skin boosters are popular for enhancing skin health, clinical evidence supporting their effectiveness remains limited. Injectable products show potential in revitalizing skin, but safety concerns persist due to challenges in sterilization and the risk of biological contamination. Traditional methods of sterilization (heat and irradiation) can denature collagen. This study addresses these issues by introducing a novel technique: the double filtration and low-temperature steam sterilization of a collagen gel. In vitro tests documented the sterility and confirmed that the collagen did not show cytotoxicity, degradation, integrity, and viscosity characteristics changes after the processing and sterilization. The collagen gel induced new collagen expression and the proliferation of human dermal fibroblasts when the cells were cultured with the collagen gel. An in vivo study found no adverse effects in rats or significant lesions at the implantation site over 13 weeks. These results suggest that this novel method to process collagen gels is a safe and effective skin booster. Advanced processing methods are likely to mitigate the safety risks associated with injectable collagen products, though further research is needed to validate their biological effectiveness and clinical benefits.

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Introduction to soft tissue fillers

Cited by 3 publications

References 15 publications

Legal analysis of South Korean cosmetic filler litigations for safer medical practices

Legal analysis of South Korean cosmetic filler litigations for safer medical practices

Between Beauty and the Law: Analyzing Cosmetic Filler Litigations in South Korea for Safer Medical Practices

Biocompatibility Study of Purified and Low-Temperature-Sterilized Injectable Collagen for Soft Tissue Repair: Intramuscular Implantation in Rats

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