Introduction to Nanoparticulate Drug Delivery Systems

Patel, Jayvadan K.; Patel, Anita; Patel, M. P.; Vyas, Govind

doi:10.1007/978-3-030-83395-4_1

Cited by 5 publications

(2 citation statements)

References 113 publications

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“…In comparison to metallic nanoparticles, polymeric nanoparticles are soft, more flexible, and less dense, allowing for these particles to be more malleable for therapeutic drug encapsulation 87 . Various properties of polymeric nanoparticles, such as their dimension, external charge with aspect ratio could be altered to meet the demand of broad spectrum of drugs 88 . Polymeric nanoparticles undergo a process called endocytosis, which involves the engulfment of the nanoparticles by the accepting cell’s membrane to cross the blood brain barrier (BBB) 89 .…”

Section: Applicationsmentioning

confidence: 99%

Nanomedicines: A Focus on Nanomaterials as Drug Delivery System with Current Trends and Future Advancement

et al. 2022

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The rapid advancement of nanomedicine presents novel alternatives that have the potential to transform health care. Targeted drug delivery as well as the synthesis of nanocarriers is a growing discipline that has been intensively researched to reduce the complexity of present medicines in a variety of diseases and to develop new treatment and diagnostic techniques. There are several designed nanomaterials used as a delivery system such as liposomes, micelles, dendrimers, polymers, carbon-based materials, and many other substances, which deliver the drug moiety directly into its targeted body area reducing toxic effect of conventional drug delivery, thus reducing the amount of drug required for therapeutic efficacy and offering many more advantages. Currently, these are used in many applications, including cancer treatment, imaging contrast agents, and biomarker detection and so on. This review provides a comprehensive update in the field of targeted nano-based drug delivery systems, by conducting a thorough examination of the drug synthesis, types, targets, and application of nanomedicines in improving the therapeutic efficiency.

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Section: Applicationsmentioning

confidence: 99%

Nanomedicines: A Focus on Nanomaterials as Drug Delivery System with Current Trends and Future Advancement

et al. 2022

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“…able for therapeutic drug encapsulation [87]. Various properties of polymeric nanoparticles, such as their dimension, external charge with aspect ratio could be altered to meet the demand of broad spectrum of drugs [88]. Polymeric nanoparticles undergo a pro cess called endocytosis, which involves the engulfment of the na noparticles by the accepting cell's membrane to cross the blood brain barrier (BBB) [89].…”

Section: Cns Disordersmentioning

confidence: 99%