India is a gifted country with rich biodiversity and treasure of medicinal plants. From the ancient times various plants have been using for healthcare. Among them, very few were studied systematically so far. Lantana camara is a flowering ornamental and evergreen plant found throughout India. The plant has evoked a lot of interests among the researchers due to its diversified pharmaceutical potential. The Plant is reported to be used in traditional medicine system since very long time for the treatment of various ailments including itches, cuts, ulcers, swellings, bilious fever, cataract, eczema and rheumatism. In last few decades, scientists and researchers have investigated on different parts of the plants. In continuous investigations on this plant, it has been observed that various parts of the plant are used in the treatment of cold, headache, chicken pox, eye injuries, whooping cough, asthma, bronchitis and arterial hypertension. These studies established the therapeutic potential of Lantana camara in modern medicines and considered to be promising candidate for the drug discovery. The current review has deeper focus on Taxonomy, Geographical distribution, phytochemical studies, pharmacological activities and toxicology of Lantana camara.