Introduction. Calcium signals and developmental patterning

Whitaker, Michael; Smith, James C.

doi:10.1098/rstb.2007.2248

Cited by 11 publications

(5 citation statements)

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“…Another important well-known fact is that the emergence and passage of dozens (up to 50) of waves of an increased concentration of calcium ions released from the endoplasmic reticulum depot is the essential condition for fertilization throughout the entire ovum volume [ 104 ]. The mechanisms of realization and the physiological necessity of this are still unknown, although the phenomenon has been actively studied for many years [ 105 , 106 ], but one thing is clear that LILI realizes its biomodulating properties through activation of Ca 2+ -dependent intracellular reactions, activating the same calcium depot.…”

Section: Experimental Researchmentioning

confidence: 99%

Effectiveness of low level laser therapy for treating male infertility

Moskvin¹,

Аполихин²

2018

BioMedicine

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In half of the cases, the infertility of the couple is due to the disorder of the male fertility. The leading factors that cause male infertility are urogenital infections, disorders of the immune system, testicular and prostate pathology, as well as endocrine disorders.Low level laser therapy (LLLT) is a very effective physical therapy method, used in many areas of medicine, including obstetrics and gynaecology, andrology and urology; and it is recommended as an integral part of the complex treatment of infertility.The literature review showed that LLLT is beneficial in treating male infertility. Laser can significantly improve the survival, motility and speed of movement of spermatozoa. Laser therapy of patients with prostatitis and vesiculitis can eliminate infiltrative-exudative changes, improve reproductive and copulatory functions. Local illumination of red (635 nm) and infrared (904 nm) spectra should be combined with intravenous laser blood illumination (ILBI) of red (635 nm) and ultraviolet (UV) (365 nm) spectra.

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Section: Experimental Researchmentioning

confidence: 99%

Effectiveness of low level laser therapy for treating male infertility

Moskvin¹,

Аполихин²

2018

BioMedicine

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“…Исходя из известных обобщенных соображений, в частности понимания биофизи-ки процессов поглощения и рассеяния лазерного света, для клинической практики чаще всего вы- [31,51]. Выбор данных спектральных диапазонов опре-деляется также тем, что именно в областях 600-650 и 850-900 нм наиболее выражено поглощение света сперматозоидами [48,49].…”

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“…Вероятно, имеет значение и тот известный факт, что обязательным условием оплодотворения явля-ется возникновение и прохождение по всему объ-ему яйцеклетки десятков (до 50) волн повышенной концентрации ионов кальция, высвобождающе-гося исключительно из депо эндоплазматического ретикулума [51]. Механизмы реализации и физио-логическая необходимость этого процесса неиз-вестны до сих пор, хотя активно изучаются много лет, но понятно одно, что НИЛИ реализует свои биомодулирующие свойства именно через актива-цию Ca…”

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Experimental justification of laser therapy efficiency of men's infertility

et al. 2017

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Male infertility is a multifactorial syndrome, which includes a wide range of disorders. It is a symptom of many different pathological conditions affecting both the reproductive and other body systems: endocrine, nervous, blood-vascular, and immune systems. Low level laser therapy is a method of modern physiotherapy, in which the impact is carried out by low-intensity laser irradiation (LILI). It is widely used in all areas of modern medicine, due to its high efficiency, simplicity of use, the absence of contraindications and side effects. The results of russian and foreign experimental studies on the article subject were analyzed. A definite conclusion is drawn that low level laser therapy should be used as much as possible in the complex treatment of men with infertility, since the effectiveness of the method is not just high, but often has no alternatives. At the same time, the available low level laser therapy techniques should be widely used: locally, rectally, laser acupuncture, ILBI (intravenous laser blood irradiation), on the projection of various organs, paravertebrally, etc. All parameters of laser action should be set (wavelength; mode of operation; frequency for pulsed lasers; power; power density, determined by the method of exposure; exposure, localization), which are specified by the relevant regulatory documents and clinical recommendations. (For citation: Moskvin SV, Borovets SJu, Toropov VA. Experimental justification of laser therapy efficiency of men's infertility. Urologicheskie vedomosti. 2017;7(4):44-53. doi: 10.17816/uroved7444-53).

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“…The most familiar case is the neuron action potential, the electrical aspects of which make it easy to detect by primitive means, even though it is fundamentally a reactiondiffusion wave 23 . But there are also non-electrical varieties: cAMP waves in slime molds, which direct the colony's organization into fruiting bodies 24 ; calcium waves, directly implicated in oogengenesis 25,26 , developmental patterning 27 , brain function [28][29][30] , and cell signaling in animals 31 and plants 32 ; and MinDE waves in E. coli, perhaps the most important of all because they are involved in a bacterial length decision 33 . All of these non-electrical versions require highly advanced technologies to see, and also required a bit of luck to find, so there is good reason to suspect that more exist and simply have not been detected yet.…”

Section: Chemical Potential Wavesmentioning

confidence: 99%

Critical waves and the length problem of biology

Laughlin

2015

Proc. Natl. Acad. Sci. U.S.A.

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It is pointed out that the mystery of how biological systems measure their lengths vanishes away if one premises that they have discovered a way to generate linear waves analogous to compressional sound. These can be used to detect length at either large or small scales using echo timing and fringe counting. It is shown that suitable linear chemical potential waves can, in fact, be manufactured by tuning to criticality conventional reaction-diffusion with a small number substance. Min oscillations in Escherichia coli are cited as precedent resonant length measurement using chemical potential waves analogous to laser detection. Mitotic structures in eukaryotes are identified as candidates for such an effect at higher frequency. The engineering principle is shown to be very general and functionally the same as that used by hearing organs.growth and form | waves | laser amplifier | MinDE | mitosis I t is not known how living things measure their lengths. This is true notwithstanding the immense progress made over the past 30 y in understanding morphogen gradients in embryogenesis (1-6). The problem is captured nicely by the confusion over regulation of the bicoid profile in Drosophila (7-11), but it is also reflected in the notorious instability, hysteresis, and lack of scalability of traditional static reaction-diffusion (12, 13). No one knows why cells are the size they are (14), why plants and animals are the size they are (15), how organs grow maintaining their proportions (16), and how some animal bodies regenerate lost limbs (17). On the matter of length determination, per se, very little progress has been made beyond Thompson's 1917 treatise on biological form (18).Length has a special place in biology by virtue of being a primitive quantity with units. It is not possible for living things to size themselves properly without having developed the skill of measuring these quantities as numbers and relating these numbers to each other mathematically. They require meter sticks to do this. They must fabricate these meter sticks using diffusion and motors, because they are the only biochemical elements that involve length. The relationships of these meter sticks to each other and to the lengths they measure must be precise and described by equations. This is because precise mathematical relationships among lengths are what size and shape are.In this paper I point out that the difficulty of accounting for length relationships of parts of organisms with equations disappears instantly if the organism is premised to have discovered a way to emulate elementary physical law. In particular, one simple invention is sufficient to facilitate the measurement and construction of body plans of any shape and size one might wish in a way that is both plastic and scalable: the conversion of diffusive motion into linear waves using engines. The concept is general because all motion in the presence of disorder, including motion of cytoskeletal components, becomes diffusive at long time and length scales by virtue of evolving into a...

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Introduction. Calcium signals and developmental patterning

Cited by 11 publications

References 50 publications

Effectiveness of low level laser therapy for treating male infertility

Effectiveness of low level laser therapy for treating male infertility

Experimental justification of laser therapy efficiency of men's infertility

Critical waves and the length problem of biology

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