Introduction

Correction of tear trough deformity with a cohesive polydensified matrix hyaluronic acid: a case series

“…Several studies have analyzed data for the elasticity and viscosity of filler products that exert their effects immediately after treatment, with the intention of differentiating them and predicting their behavior during and after injection. 6 , 8 , 15 , 16 In one of these studies, rheological data for a range of HA filler products including CPM HA gel were correlated with data from tissue integration studies to provide a scientific rationale for selecting products for their appropriate clinical applications. 6 CPM HA gel had the lowest elasticity and viscosity of the tested products, which correlated with its homogeneous pattern of tissue integration after intradermal implantation.…”

“…7 Furthermore, while all HA fillers are hygroscopic, the specific crosslinking technology of CPM HA gel means that it absorbs less water post-injection and is therefore associated with very little post-injection swelling compared with other HA gels used to treat this area. 8 The gel is approved in Europe and was approved by the US Food and Drug Administration in 2011 for injection into the superficial to mid dermis for correction of facial wrinkles and folds. It produces results comparable with those of other leading HA fillers with a similar duration of effect, and is well tolerated.…”