24Objective: To evaluate if pharmacy students' participation in personal pharmacogenetic 25 (Pgx) testing enhances their knowledge and attitude towards precision medicine (PM). 26 Methods: First-year pharmacy students were offered personalized pharmacogenetic 27 testing as a supplement to a required curricular pharmacogenomics course. Ninety-28 eight of 122 (80%) students completed pre-and post-course surveys assessing 29 knowledge and attitudes regarding PM; 73 students also volunteered for personal 30 pharmacogenetic testing of the following drug metabolizing enzymes (CYP2C19, 31 CYP2D6, UGT1A1) and pharmacodynamics-relevant proteins (interleukin (IL)-28B & 32 human lymphocyte antigen HLAB*5701). 33 Results: Using a linear mixed effects model, we observed statistically significant 34 improvements in 100% of knowledge and 70% of attitude-related questions for students 35 who decided to undergo personal pharmacogenetic testing. 36 Conclusion: Personal pharmacogenetic testing significantly enhances knowledge of 37 and attitude related to precision medicine among PharmD trainees. This study 38 demonstrates the feasibility and importance of educating future pharmacists by 39 incorporating pharmacogenetic testing into professional school curricula. 40 41