Introducing New Peptide Extracts from <i>Saccharomyces cerevisiae</i> and <i>Achatina achatina</i> Fluids with Strong Inhibitory Activities on Human <i>α</i>-Amylase

Abstract

This study aimed at exploring for new natural peptides with strong inhibitory capabilities on α-amylase, the main metabolic enzyme that regulates mellitus diabetes, in order to contribute in controlling this global pandemic. It has consisted in heat shock (to 60˚C, 70˚C, 80˚C, 90˚C and 100˚C for 10, 20 and 30 minutes) of crude proteins extracted from biomass and extracellular parts of Saccharomyces cerevisiae under cultivation, and from the digestive fluid of the giant snail Achatina achatina, and in-vitro assays of the resulting solutions, as effectors, in human α-amylase catalyzing reactions. The results showed