Introducing Fe3O4@SiO2@KCC-1@MPTMS@CuII catalytic applications for the green one-pot syntheses of 2-aryl(or heteroaryl)-2,3-dihydroquinazolin-4(1H)-ones and 9-aryl-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-diones

Galehban, Morteza Hasanpour; Zeynizadeh, Behzad; Mousavi, Hossein

doi:10.1016/j.molstruc.2022.134017

Cited by 11 publications

(1 citation statement)

References 162 publications

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“…In this regard, the design and/or use of simple and efficient synthetic strategies for the preparation of such precious compounds is worthwhile. One-pot multi-component reactions (MCRs) are in a unique and valuable class of chemical reactions owing to their outstanding properties such as safety, convenience, efficiency, economics, and many others, which can be used for this purpose …”

Section: Introductionmentioning

confidence: 99%

Practical Three-Component Regioselective Synthesis of Drug-Like 3-Aryl(or heteroaryl)-5,6-dihydrobenzo[h]cinnolines as Potential Non-Covalent Multi-Targeting Inhibitors To Combat Neurodegenerative Diseases

Mousavi,

Rimaz,

Zeynizadeh

2024

ACS Chem. Neurosci.

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Neurodegenerative diseases (NDs) are one of the prominent health challenges facing contemporary society, and many efforts have been made to overcome and (or) control it. In this research paper, we described a practical one-pot two-step three-component reaction between 3,4-dihydronaphthalen-1(2H)one (1), aryl(or heteroaryl)glyoxal monohydrates (2a−h), and hydrazine monohydrate (NH 2 NH 2 •H 2 O) for the regioselective preparation of some 3-aryl(or heteroaryl)-5,6-dihydrobenzo[h]cinnoline derivatives (3a−h). After synthesis and characterization of the mentioned cinnolines (3a−h), the in silico multi-targeting inhibitory properties of these heterocyclic scaffolds have been investigated upon various Homo sapiens-type enzymes, including

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Section: Introductionmentioning

confidence: 99%

Practical Three-Component Regioselective Synthesis of Drug-Like 3-Aryl(or heteroaryl)-5,6-dihydrobenzo[h]cinnolines as Potential Non-Covalent Multi-Targeting Inhibitors To Combat Neurodegenerative Diseases

Mousavi,

Rimaz,

Zeynizadeh

2024

ACS Chem. Neurosci.

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Titanium Tetrachloride‐Based Ionic Liquids Immobilized on Mesoporous Fe‐MCM‐41 for the Heterogeneous Cooperative Synthesis of Dihydroquinazolinones

Hu,

Rong,

Chen

et al. 2023

ChemistrySelect

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In this study, we report a successful strategy for the generation of a type of multifunctional heterogeneous supported ionic liquids catalysts. The synthesized supported ionic liquids (Fe‐MCM‐41/IL) were used in the catalytic cyclocondensation of 2‐aminobenzamide and various ketones and aldehydes towards the efficient synthesis of the dihydroquinazolinones under green conditions. The influence of the different catalysts and reaction parameters on the catalytic behaviors were sufficiently investigated. The supported catalyst (2)Fe‐MCM‐41/IL(0.6) showed the optimal catalytic efficiency. A hot filtration experiment revealed that the reaction proceeded in a heterogeneous pathway. The catalytic activity of (2)Fe‐MCM‐41/IL(0.6) could be maintained efficiently after recycling up to five consecutive runs under the optimized reaction conditions. Merits of this meticulously designed protocol are the use of novel supported catalyst, easy work‐up process, feasibility and sustainability, indicating its potential industrial application prospect.

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Fabrication of novel magnetic ionogel catalyst for one-pot synthesis of pyranopyrazole derivatives at ambient temperature

Shojaee,

Azizi,

Mirjafary

et al. 2023

J Sol-Gel Sci Technol

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Introducing Fe3O4@SiO2@KCC-1@MPTMS@CuII catalytic applications for the green one-pot syntheses of 2-aryl(or heteroaryl)-2,3-dihydroquinazolin-4(1H)-ones and 9-aryl-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-diones

Cited by 11 publications

References 162 publications

Practical Three-Component Regioselective Synthesis of Drug-Like 3-Aryl(or heteroaryl)-5,6-dihydrobenzo[h]cinnolines as Potential Non-Covalent Multi-Targeting Inhibitors To Combat Neurodegenerative Diseases

Practical Three-Component Regioselective Synthesis of Drug-Like 3-Aryl(or heteroaryl)-5,6-dihydrobenzo[h]cinnolines as Potential Non-Covalent Multi-Targeting Inhibitors To Combat Neurodegenerative Diseases

Titanium Tetrachloride‐Based Ionic Liquids Immobilized on Mesoporous Fe‐MCM‐41 for the Heterogeneous Cooperative Synthesis of Dihydroquinazolinones

Fabrication of novel magnetic ionogel catalyst for one-pot synthesis of pyranopyrazole derivatives at ambient temperature

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