Introducing a novel in vivo method to access visual performance during dewetting process of contact lens surface

Kolbe, Oliver; Zimmermann, Felix; Marx, Sebastian; Sickenberger, Wolfgang

doi:10.1016/j.clae.2020.02.011

Cited by 8 publications

(12 citation statements)

References 31 publications

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“…This is performed using an image (keratoscopy, videokeratoscopy, grid, etc.) projected onto the contact lens and evaluating the quality of the reflection from the PLTF [102,[106][107][108][109][110][111][112][113][114][115]. NIBUT of the PLTF can also provide contact lens practitioners with an indirect assessment of the lubricity and thus potentially on-eye friction of the contact lens, which is impossible to measure directly in the eye [116].…”

Section: Measuring Wettability In Vivomentioning

confidence: 99%

BCLA CLEAR - Contact lens wettability, cleaning, disinfection and interactions with tears

Willcox

Keir

Maseedupally

et al. 2021

Contact Lens and Anterior Eye

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Contact lens materials have undergone significant changes over the past 20 years, particularly with respect to the introduction of silicone hydrogel materials. Whilst this development addressed hypoxic issues, other important areas relating to contact lens success, notably comfort, require further research.Contact lens wettability remains a crucially important part of biocompatibility. Contact lenses can be made more wettable by incorporation of surfactants into blister packs, internal wetting agents, surface treatments or care solutions. However, there remains no clear association between contact lens wettability and comfort, making it challenging to determine the potential for these approaches to be of significant clinical benefit. Most contact lenses are used on a daily wear, reusable basis, which requires them to be disinfected when not worn. The ideal disinfecting solution would also improve comfort during wear. However, balancing these requirements with other factors, including biocompatibility, remains a challenge. Soft lens materials invariably take up and subsequently release certain components of disinfecting solutions onto the ocular surface. This may affect tear film stability and the normal ocular microbiome, and further research is needed in this area to determine whether this has any affect on comfort. Finally, contact lens materials sorb components of the tear film, and these interactions are complex and may change the biochemistry of the tear film, which in turn may affect their comfort.In conclusion, the interaction between lens materials, tear film and disinfection solution plays an important role in the biocompatibility of lenses. However, the exact role and whether this can be altered to improve biocompatibility and comfort during wear remains debatable. This report summarises the best available evidence to examine this complex relationship and the opportunities for practitioners to enhance in-eye comfort of contemporary lenses, along with providing suggestions for areas of study that may provide further information on this topic.

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Section: Measuring Wettability In Vivomentioning

confidence: 99%

BCLA CLEAR - Contact lens wettability, cleaning, disinfection and interactions with tears

Willcox

Keir

Maseedupally

et al. 2021

Contact Lens and Anterior Eye

View full text Add to dashboard Cite

show abstract

“…All these factors would not allow the relationship between visual quality and wettability to be clearly established. In order to evaluate both parameters simultaneously during contact lens wear, Kolbe et al [32] recently modified a commercial topographer to analyze the relationship of dewetting time and area with the subject's visual acuity loss after blinking.…”

Section: Discussionmentioning

confidence: 99%

Stabilization of comfort and visual quality after the insertion of soft contact lenses

Carpena-Torres

Pastrana

Rodríguez-Pomar

et al. 2022

Contact Lens and Anterior Eye

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“…It has been reported in the literature that there is a relationship between the distribution and stability of tear lm visual acuity [23]. Since NIBUT determines tear instability by evaluating topographic regularity indices, it also measures the anatomical function of the tear, as well as its physiological function.…”

Section: Discussionmentioning

confidence: 99%

Ability of non-invasive tear break-up time to determine tear instability in contact lens wearers

Muhafız

Demir

2021

Int Ophthalmol

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Purpose To evaluate the performance of precorneal and prelens non-invasive tear break-up time (NIBUT) measurements to determine tear instability in contact lens (CL) wearers.Methods In this study 50 eyes of CL wearers were evaluated. Precorneal rst and average NIBUTs and uorescein tear break-up time (FBUT) were measured before wearing CLs in the morning. Those with FBUT less than 10 seconds were considered to have tear instability. After wearing CL, rst and average prelens NIBUTs were measured at the 30th minute. The receiver operating characteristic (ROC) curve was analyzed to evaluate the performance of NIBUT measurements in the diagnosis of tear instability. ResultsThe FBUT value had a signi cant correlation with rst and average precorneal NIBUT values (p < 0.001, r = 0.653 and p < 0.001, r = 0.628,respectively). The FBUT value had no correlation with the prelens rst and average NIBUT values (p = 0.542 and p = 0.263,respectively). To understand the relationship between the precorneal and prelens NIBUT values measured by the automated method, their correlation was evaluated. There was no signi cant correlation between the precorneal and prelens NIBUTs (for all;p > 0.05).The area under curve (AUC) in ROC curve for the rst and average precorneal NIBUTs were 0.842 (p<0.001) and 0.810 (p<0.001), respectively. The AUC values for the rst and average prelens NIBUTs at the 30 th minute of CL wear were 0.586 and 0.619 respectively (p=0.317 and p=0.166, respectively).Conclusions: Precorneal NIBUT measurements may be useful in diagnosing tear instability in CL wearers.Prelens NIBUT values are not yet capable of adequately de ning the tear lm dynamics.

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Introducing a novel in vivo method to access visual performance during dewetting process of contact lens surface

Cited by 8 publications

References 31 publications

BCLA CLEAR - Contact lens wettability, cleaning, disinfection and interactions with tears

BCLA CLEAR - Contact lens wettability, cleaning, disinfection and interactions with tears

Stabilization of comfort and visual quality after the insertion of soft contact lenses

Ability of non-invasive tear break-up time to determine tear instability in contact lens wearers

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