Intrinsically photosensitive retinal ganglion cell mediated pupil function is impaired in Parkinson’s disease

Abstract

26Parkinson's disease is characterised by non-motor symptoms including sleep and circadian 27 disruption, but the underlying aetiology is not well understood. Melanopsin-expressing 43Both groups exhibited similar pupillary unrest in darkness. 44We show that melanopsin and the rod/cone-photoreceptor contributions to the pupil control