Intrinsic MRI contrast from amino acid-based paramagnetic ionic liquids

Gehlot, Praveen Singh; Gupta, Hariom; Rathore, Mangal S.; Khatri, Kapil; Kumar, Arvind

doi:10.1039/d0ma00339e

Cited by 7 publications

(15 citation statements)

References 56 publications

(62 reference statements)

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“…They have conducted a proton nuclear magnetic relaxation dispersion 1 Reproduced from Ref. [63] with permission from Royal Society of Chemistry respectively.…”

Section: Paramagnetic Ionic Liquids As Contrast Agentsmentioning

confidence: 99%

“…Thus, here, aqueous solution of iron-containing PMILs is examined for imaging, and their relaxivity rate at various concentrations is studied. Kumar et al have synthesized amino-acid-based PMILs [63]. These amino acids are used in two forms-esterified and without esterified.…”

Section: Name Of Amino Acid and Chemical Structures Of Used In The St...mentioning

confidence: 99%

“…Reproduced from Ref. [63] with permission from Royal Society of Chemistry respectively. physical property is weight, then it is termed as a TGA.…”

Section: Representative Uv and Raman Spectrum Of Pmil (Proc 1 [Fecl 4 ]mentioning

confidence: 99%

“…MRI property of these PMILs is also investigated and claimed their superior contrast activity. Since these are made of amino acid and iron moiety, therefore, they are non-hazardous, toxic-metal-free and biofriendly contrast agent (Table 1) [63]. This work is patented in Indian patent office [64].…”

Section: Introductionmentioning

confidence: 99%

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Iron-Based Ionic Liquids for Magnetic Resonance Imaging Application

Gehlot¹,

Kumar²

2023

Industrial Applications of Ionic Liquids

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In the biomedical treatment, identification of diseases and their diagnosis are running with help of many biomedical techniques including imaging such as magnetic resonance imaging (MRI). MRI technique requires an identification of targeted cell or lesion area which can be achieved by contrast agent. For clinical use, T1 positive MRI contrast agents and T2 negative MRI contrast agents are being used. However, these contrast agents have several drawbacks such as toxic effect of metal centre, poor resolution, weak contrast, low intensity image and short signal for long-term in vivo measurement. Therefore, development of new contrast agents is imperative. Ionic liquids with their unique properties have been tried as novel contrasting materials. Particularly, iron-containing amino-acid-based ionic liquids or amino-acid-based paramagnetic ionic liquids (PMILs) have been reported and demonstrated as MRI contrast agents. These PMILs have shown superior features over reported contrast agents such as dual-mode contrast, biofriendly nature, involvement of non-toxic magnetic centre (Fe), stable aqueous solution, better image intensity at low concentration level and easy to synthesis. PMILs have been characterized well and studied with animal DNA using various techniques. The result revealed that animal DNA is remain safe and stable structurally up to 5 mmol.l−1. These cost-effective PMILs opened the greater opportunity in the field of contrast-based biomedical applications.

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“…They have conducted a proton nuclear magnetic relaxation dispersion 1 Reproduced from Ref. [63] with permission from Royal Society of Chemistry respectively.…”

Section: Paramagnetic Ionic Liquids As Contrast Agentsmentioning

confidence: 99%

Section: Name Of Amino Acid and Chemical Structures Of Used In The St...mentioning

confidence: 99%

“…Reproduced from Ref. [63] with permission from Royal Society of Chemistry respectively. physical property is weight, then it is termed as a TGA.…”

Section: Representative Uv and Raman Spectrum Of Pmil (Proc 1 [Fecl 4 ]mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Iron-Based Ionic Liquids for Magnetic Resonance Imaging Application

Gehlot¹,

Kumar²

2023

Industrial Applications of Ionic Liquids

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“…We have also looked at the metal-based ILs system and its applications in the past. 34 Due to their unique properties, MBILs fared well in a range of applications such as oxidative desulfurization, 35 MRI contrast agent, 36 drug delivery, 37 and catalysis, 38 etc . So, now here we looked at one of its applications in lignin chemistry, which is the selective synthesis of vanillin at room temperature.…”

Section: Introductionmentioning

confidence: 99%

Metal-based ionic liquids: effective catalysts in aqueous media for the selective production of vanillin from alkali lignin at room temperature

2022

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Industrial Applications of Ionic Liquids

Maase¹

2007

Ionic Liquids in Synthesis

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World is passing through the energy crises due to the rapid depletion of fossil fuels.To address this crisis and to fulfill the energy demands worldwide, development of energy storage devices have increased rapidly. Also, renewable energy resources are intermittent, and therefore nevertheless, this energy resources are not always available. In that context, rechargeable lithium batteries are most promising energy storage devices owing to high energy and power density. Although, the development of the component of rechargeable battery such as anode, cathode and electrolyte are in progress as they play major role in enhancing the electrochemical performance of lithium-ion battery. Among them, electrolyte plays crucial role as it provides the path for diffusion of Li + ions between the electrodes. In that context, ionic liquid-based electrolytes are widely used as it acts as plasticizer and thus increases the conductivity of electrolyte considerably. In this chapter, we have discussed basics of ionic liquids and its application in electrolyte system. Also, in this chapter, we have discussed various properties of ionic liquid-based electrolytes and their application in rechargeable lithium battery.

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Intrinsic MRI contrast from amino acid-based paramagnetic ionic liquids

Abstract: Paramagnetic ionic liquids (PMILs), comprising of natural amino acids and tetrachloroferrate (III) as constituent ions have been prepared and reported as highly efficient dual mode (T1&T2) responsive contrast agents for...

Cited by 7 publications

References 56 publications

Iron-Based Ionic Liquids for Magnetic Resonance Imaging Application

Iron-Based Ionic Liquids for Magnetic Resonance Imaging Application

Metal-based ionic liquids: effective catalysts in aqueous media for the selective production of vanillin from alkali lignin at room temperature

Industrial Applications of Ionic Liquids

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