Intrinsic Disc Pressure as a Measure of Integrity of the Lumbar Spine

Intradiscal pressure measurements in normal discs, compressed discs and compressed discs treated with axial posterior disc distraction: an experimental study on the rabbit lumbar spine model

“…Although the high range of physiological IVD pressure was not expected, the interindividual range of pressure at corresponding levels of the non-treated rabbit spine was far less extensive. Most reported studies on IVD pressure measurements examined one single disc [2,14,15,[20][21][22]30] or the adjacent discs to fusion [4,5,16,25,29]. We conclude that it is important to compare only corresponding levels of the spine with respect to intradiscal pressure measurements.…”

“…Comparable animal models applied an external load between 0.15 MPa and 1.3 MPa [10,12,15], which may be below the postulated threshold for tissue degradation. The frequency and amount of load application seems to play a crucial role in disc metabolism.…”

Effect of an internal fixator and a bone graft on intersegmental spinal motion and intradiscal pressure in the adjacent regions

“…In vitro measurements of intradiscal pressure [1,13,16,32] and intersegmental motion [2,14,24,31] have been performed previously, mostly in monosegmental specimens or in only one segment of a multisegmental Abstract Stabilizing a lumbar spine with an implant alters the mechanical properties of the bridged region. In order to determine whether this procedure is associated with higher loads in the adjacent segments, seven lumbar cadaver spines were mounted in a spine tester and loaded with pure moments of flexion/extension, left and right lateral bending, and left and right axial rotation.…”

Evaluation of Lumbosacral Angle (LSA) and its Impact on Patients with Lumbar Disc Herniation

“…In the first in vivo experiments to determine the amount of pressure inside a disc, a pressure transducer was placed inside. L3-L4 disc pressure 300% higher than normal was found at the sitting position, forward at 20 degrees flexion, or with 20 kg load [18].…”