Intrinsic and extrinsic factors that may influence DNA preservation in skeletal remains: A review

Raffone, Caterina; Baeta, Miriam; Lambacher, Nicole; Granizo-Rodríguez, Eva; Etxeberria, Francisco; Pancorbo, Marian M. de

doi:10.1016/j.forsciint.2021.110859

Cited by 12 publications

(4 citation statements)

References 85 publications

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“…Finally, although DNA profiling is an important element for the identification of human remains, several factors can affect the results of this analysis, such as an insufficient amount of extracted DNA or its degradation in cases of poorly preserved samples. In such cases, a multidisciplinary approach may be necessary that considers the use of other disciplines, including forensic anthropology and odontology [56,57].…”

Section: Discussionmentioning

confidence: 99%

Identification of the Remains of an Adult Using DNA from Their Deciduous Teeth as a Reference Sample

Chávez-Briones,

Jaramillo-Rangel,

Ancer-Arellano

et al. 2023

Medicina

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In many forensic cases, the identification of human remains is performed by comparing their genetic profile with profiles from reference samples of relatives, usually the parents. Here, we report, for the first time, the identification of the remains of an adult using DNA from the person’s deciduous teeth as a reference sample. Fragments of a skeletonized and burned body were found, and a short tandem repeat (STR) profile was obtained. A woman looking for her missing son went to the authorities. When the DNA profile of the woman was compared to a database, a positive match suggested a first-degree kinship with the person to whom the remains belonged. The woman had kept three deciduous molars from her son for more than thirty years. DNA typing of dental pulp was performed. The genetic profiles obtained from the molars and those from the remains coincided in all alleles. The random match probability was 1 in 2.70 × 1021. Thus, the remains were fully identified. In the routine identification of human remains, ambiguous STR results may occur due to the presence of null alleles or other mutational events. In addition, erroneous results can be produced by false matches with close family members or even with people who are completely unrelated to the victim, such that, in some cases, a probability of paternity greater than 99.99% does not necessarily indicate biological paternity. Whenever possible, it is preferable to use reference samples from the putative victim as a source of DNA for identification.

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Section: Discussionmentioning

confidence: 99%

Identification of the Remains of an Adult Using DNA from Their Deciduous Teeth as a Reference Sample

Chávez-Briones,

Jaramillo-Rangel,

Ancer-Arellano

et al. 2023

Medicina

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“…Taphonomic studies can therefore play a key role in the reconstruction of the postmortem transformations undergone by skeletal remains and subsequently DNA. 9 The postmortem dynamics of DNA breakdown are currently not well understood. Therefore, taphonomic investigations can be crucial in reconstructing the postmortem changes that skeletal remains and later DNA underwent.…”

Section: Literature Reviewmentioning

confidence: 99%

Victim identification through skeletal remains: A review

Yadav¹,

Kulshreshtha

Sharma³

et al. 2023

IJFMTS

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Investigative authorities use forensic anthropology to examine human skeletal remains in order to identify unidentified human remnants. Anthropology alone is the study of man, but also includes culture, language, and physical remains of humans. Forensic anthropology is used to help with the recovery of human remains and to interpret trauma. Asian, African, and European people, as well as the living and the dead, are all of interest to anthropologists. Anthropologists are also fascinated with a wide range of human characteristics, such as their technology, family dynamics, cultures, and linguistic. Forensic otology is a branch of forensic anthropology. The field began in the 19th century. Mathieu or fill published a textbook on measurements of arm bones in 1835. E.A Bertillon proposed an anthropometric system for personal identification in 1885. A branch of physical anthropology is forensic anthropology. In this analysis, criminal cases are solved using skeletal analysis and other archaeology methods. Experts in forensic anthropology focus on examining hard tissues like bones. They are also skilled at locating and recovering buried bodies. In this review we are going to discuss about the ways of identification of a victim by found skeletal remains

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“…Nejčastějším zdrojem DNA pro analýzu příbuzenských vztahů nebo jako srovnávací materiál při identifikaci neznámého těla je stěr z bukální sliznice. V praxi se dále používají různé typy tkání zajištěné při pitvě neznámého těla, případně biologické stopy zajištěné Policií ČR (63).…”

Section: Procesní Diagramunclassified

Vybrané metody forenzní genetiky

2022

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Intrinsic and extrinsic factors that may influence DNA preservation in skeletal remains: A review

Cited by 12 publications

References 85 publications

Identification of the Remains of an Adult Using DNA from Their Deciduous Teeth as a Reference Sample

Identification of the Remains of an Adult Using DNA from Their Deciduous Teeth as a Reference Sample

Victim identification through skeletal remains: A review

Vybrané metody forenzní genetiky

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