Intravoxel Incoherent Motion Diffusion-weighted Imaging of Multiple Myeloma Lesions: Correlation with Whole-Body Dynamic Contrast Agent–enhanced MR Imaging

Abstract

Diffuse bone marrow involvement is associated with increased D. Hypervascular focal lesions with high maximal enhancement value of focal lesions also show high f value. Likewise, the decreased maximal enhancement value of focal lesions after treatment is accompanied by decreased f.

Intravoxel incoherent motion diffusion‐weighted imaging of bone marrow in patients with acute myeloid leukemia: a pilot study of prognostic value

“…Studies have indicated that the high f value of the head and neck malignant tumor suggests poor prognosis . Bourillon and other studies on multiple myeloma showed that f value of bone marrow lesions was positively correlated with the maximum enhancement degree of the tumor. Compared with the CR group, high cellularity of the bone marrow and more blood supply could cause higher bone marrow blood flow in NR group.…”

Utility of histogram analysis of apparent diffusion coefficient maps obtained using 3.0T MRI for distinguishing uterine carcinosarcoma from endometrial carcinoma

“…Agreement was interpreted according to the interclass correlation coefficient as: 0, poor; 0.01-0.20, minor; 0.21-0.40, fair; 0.41-0.60, moderate; 0.61-0.80, major; and 0.81-1.00, almost perfect. 17 We used the Mann-Whitney test to compare sizes of the areas of the ROIs, ADC values, kurtosis, and skewness between uterine carcinosarcomas and endometrial carcinomas, with P < 0.05 considered statistically significant. We performed receiver operator characteristic (ROC) curve analyses based on positive test results for patients with carcinosarcomas to identify the optimal cutoff for maximizing the sum of sensitivity and specificity, and we examined the area under the ROC curve (AUC) to assess the diagnostic abilities of ADC values, kurtosis, and skewness.…”

“…All measurements were correlated with those provided by the first observer, and concordance of interobserver variability was tested by calculating Spearman and interclass correlation coefficients. Agreement was interpreted according to the interclass correlation coefficient as: 0, poor; 0.01–0.20, minor; 0.21–0.40, fair; 0.41–0.60, moderate; 0.61–0.80, major; and 0.81–1.00, almost perfect …”

Measurements of Diffusion and Perfusion in Vertebral Bone Marrow Using Intravoxel Incoherent Motion (IVIM) With Multishot, Readout‐Segmented (RESOLVE) Echo‐Planar Imaging

“…As a result, the IVIM technique can now be applied to various tissues. Surprisingly, however, only a very limited number of IVIM studies have been performed on bone marrow . This might be due to lipids, which represent a major confounding factor in the quantification of both diffusion and perfusion .…”