Intravoxel incoherent motion and dynamic contrast-enhanced MRI for differentiation between hepatocellular adenoma and focal nodular hyperplasia

Abstract

In this exploratory study, K and D were able to differentiate HCAs from FNHs in most cases, whereas V, ADC and TIC analysis were not. Advances in knowledge: Histological differences between HCAs and FNHs can be quantified on MRI using K and D.

Intrahepatic cholangiocarcinoma in the setting of HBV-related cirrhosis: Differentiation with hepatocellular carcinoma by using Intravoxel incoherent motion diffusion-weighted MR imaging

“…The cellularity of ICC is relatively small and the existed tumor cell could arrange into acinar like structures, thus, which could further prompt the water molecular diffusion and increase the ADC and ADC slow value. Previous studies compared the ADC value of ICC and normal hepatic parenchyma and showed that the value of ICC was lower than the normal hepatic tissue [ 29 ], and some other studies also reported that the ADC value of the HCC was also lower than that of the relatively low cellularity benign nodules [ 30 , 31 ]. These current results were consistent with the findings that low cellularity tumor demonstrated a high ADC value compared with the high cellularity tumor.…”