Intravitreal Injection Of The Granulocyte-Colony Stimulating Factor For The Treatment Of Non-Arteritic Anterior Ischemic Optic Neuropathy: A Pilot Study

Aghdam, Kaveh Abri; Aghajani, Ali; Khorasani, Maryam; Sanjari, Mostafa Soltan; Chaibakhsh, Samira; Habibi, Abbas; Falavarjani, Khalil Ghasemi

doi:10.1080/08820538.2021.1896749

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“…While intravitreal anti-vascular endothelial growth factor (VEGF) therapy, used widely for the treatment of ischemic conditions of the retina, initially was reported as a promising treatment for NAION ( 30 ), no benefit was demonstrated in a non-randomized controlled trial ( 31 ). Intravitreal administration of QPI-1007 (a small interference RNA designed to inhibit expression of caspase 2) ( 32 ) and G-CSF ( 33 ) also have not demonstrated benefit.…”

Section: Clinical Researchmentioning

confidence: 99%