Intraventricular tuberculoma: A case report

Abstract

Intracranial tuberculomas are one of the most serious formsof tuberculosis disease after meningitis tuberculosis. It incidence varies around 0.15% -0.18% in the development world to 5% -30% of intracranial masses in some under developments areas. These tuberculomas, of course ubiquitous, are mostly diagnosed in the adulthood and usually located in the cerebellum and the cerebral hemispheres. Intra ventricular involving is uncommon and just 10 cases had been described in the literature. We report a case of an intraventricular tuberculoma in a 26-year-old man and we discuss the pathogenesis and the radiological findings according this location.

Intracranial tuberculoma in human immunodeficiency virus-infected patient: a case report

“…9 The incidence of intracranial tuberculoma range from 0.15-0.18% in developed countries and contribute to 5-30% of all space-occupying lesion in underdeveloped countries. 4 Tuberculoma which consist of necrotic caseous tissue surrounded by a capsule made of fibroblast, lymphocyte infiltrate, giant cells, and epithelioid cells seen more commonly in adult under 40 years of age. 8 Evidence also showed that development of tuberculoma is related to degree of immunosuppression, as the risk of bacterial invasion to brain depends on host immune response.…”

“…3 The most common clinical presentations are headache, nausea, vomiting, ataxia, diplopia, motor weakness, and seizure. [4][5][6][7] Since these symptoms are not specific and often resemble other intracranial space occupying lesion, intracranial tuberculoma should always be suspected in patient with tuberculosis experiencing symptoms of increased intracranial pressure. 2,3 Treatment of tuberculoma consist of anti-tuberculosis regimen, symptomatic treatment and surgical resection of the lesion.…”

Intraventricular Tuberculoma with Profound Visual Loss: A Case Report and Literature Review

“…A variety of treatment modalities had been attempted, as shown in Table 1 . Five authors opted for prior surgical excision especially when the diagnosis was doubted [ 7 - 9 , 11 - 12 ]. This was due to the rarity of the tumor location or the absence of the systemic manifestation of tuberculosis infection.…”

“…The lesion may also be imitating malignancy, as there were no specific clinical signs suggesting intraventricular tuberculoma. These patients were started on anti-tuberculosis treatment after a histopathology study confirmed tuberculoma [ 7 - 9 , 11 ].…”

“…Most of the published cases presented with features of hydrocephalus [ 3 - 10 , 12 - 14 ]. Six of these patients underwent cerebral spinal fluid redirection procedures, which included a ventriculoperitoneal shunt and external ventricular drainage [ 3 - 4 , 6 , 9 , 13 - 14 ]. Our patient was treated conservatively with an anti-tuberculosis regime and intravenous dexamethasone because she declined a ventriculoperitoneal shunt and further surgical intervention.…”