Intraventricular craniopharyngioma: a case report

Diniz, Lee Van; Jorge, Luiz Antônio; Rodrigues, Lucas Padilha; Veloso, Julia de Castro Vieira; Yamashita, Seizo

doi:10.15406/jnsk.2018.08.00306

Cited by 5 publications

(11 citation statements)

References 7 publications

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“…If the development of this pial membrane is delayed, the cells of the Rathke's pouch come into direct contact with the neuroectoderm of the developing cerebral vesicle. These cells, when they grow to form a tumor, give rise to a purely intraventricular craniopharyngioma (5,8,24). The incidence of purely IVCrs among craniopharyngioma patients in our series was 4.27% (25 purely intraventricular craniopharyngiomas out of a total of 585 craniopharyngioma patients who underwent surgery).…”

Section: Discussionmentioning

confidence: 54%

“…In our series of 25 patients, however, 60% of tumors were predominantly cystic in nature. This could be because most series report cases in adults, whereas our series The differential diagnoses of IVCs includes other lesions of the third ventricle such as colloid cysts, ependymoma, choroid plexus papilloma, hypothalamic glioma, meningioma, germinoma, and lymphoma (3,5,8,10,15,19,23).…”

Section: Discussionmentioning

confidence: 84%

“…Craniopharyngiomas are benign tumors, originating either from squamous epithelial cell that rests in the Rathke's pouch, located along its path from the nasopharynx to the infundibulum, or as a result of squamous metaplasia from the pars tuberalis of the pituitary gland (1)(2)(3)(4). They constitute 2-4% of all intracranial tumors (3,(5)(6)(7)(8)(9)(10)(11)(12). Multiple classification systems (based on their imaging features) have been proposed to help in choosing the appropriate management strategy (13).…”

Section: Introductionmentioning

confidence: 99%

“…Multiple classification systems (based on their imaging features) have been proposed to help in choosing the appropriate management strategy ( 13 ). Purely intraventricular variety of craniopharyngiomas are infrequent, with the reported incidence varying from 0.5 to 14% of all craniopharyngiomas ( 3 , 5 , 8 , 12 , 14 ). As IVCrs originate from ectopic remnants present within the neuraxis, they are generally seen in older patients and present more often with features of raised intracranial pressure, rather than with visual or endocrinological disorders, as compared with their sellar/suprasellar or suprasellar–intraventricular counterparts ( 5 , 11 , 12 , 15 ).…”

Section: Introductionmentioning

confidence: 99%

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Intraventricular Craniopharyngiomas—Overcoming Their Relative Inaccessibility: Institutional Experience With a Review of Literature

et al. 2021

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Introduction: Craniopharyngiomas constitute 2–4% of intracranial neoplasms. Intraventricular craniopharyngiomas (IVCrs) are the rarely encountered varieties of these lesions.Objective: The objective of the study was to study the special features in clinical presentation, imaging, management, and surgical outcome of IVCrs.Materials and Methods: This retrospective analysis included the combined experience from two tertiary care institutions. Medical records of histopathologically proven cases of IVCrs from January 1994 to June 2021 were assessed, and images were analyzed based on the criteria by Migliore et al. for inclusion of solely intraventricular lesion with the third ventricular ependyma demarcating it from the suprasellar cistern.Results: Among the 25 patients included (mean age: 35.4 years), the most common presentation included headache (n = 21, 84%), vomiting and other features of raised ICP (n = 18, 72%), visual complaints (n = 12, 48%), and endocrinopathies (n = 11, 44%). Fifteen had predominantly cystic tumors, two were purely solid, and eight were of mixed consistency. Primary open microsurgical procedures were performed in 18 (72%) patients, of which four (16%) were endoscope-assisted. Seven (28%) underwent a purely endoscopic procedure. One underwent a staged surgery with endoscopic cyst fenestration and intracystic interferon (IFN)-alpha therapy, followed by microsurgical excision. Complete excision was achieved in 10 patients, near-total in nine, and partial excision in six. Four patients underwent a ventriculoperitoneal shunt (one before the definitive procedure). At a median follow-up of 36 months (range:11–147 months), five patients developed a recurrence, and one had a stable small residue. This patient and two others with small cystic recurrences were observed. One patient was managed with radiotherapy alone. Another underwent re-surgery after a trial of radiotherapy, and the last patient developed a local recurrence, which was managed with radiotherapy; he then later developed an intraparenchymal recurrence, which was operated.Conclusion: Purely IVCrs present with raised intracranial pressure, and visual disturbances are less common. Their deep-seated location and limited surgical field-of-view makes minimally invasive endoscopic-assisted surgery most suitable for their excision. The thin-walled cystic lesions may be occasionally adherent to the ependymal wall in close vicinity to the thalamus–hypothalamus complex, making complete excision difficult. Their responsiveness to radiotherapy, often leads to a gratifying long-term outcome.

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Section: Discussionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Intraventricular Craniopharyngiomas—Overcoming Their Relative Inaccessibility: Institutional Experience With a Review of Literature

et al. 2021

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“…The integrity of the third ventricular floor has long been recognized as an important radiologic criterion which helps to differentiate between a purely IVCr and one that is primarily suprasellar but with an intraventricular extension (41). Migliore et al described the other commonly accepted radiologic criteria for purely IVCrs: a patent suprasellar cistern, an intact pituitary stalk, and the absence of sellar abnormalities (8,16). Pascual et al proposed that two important signs can significantly correlate with the topographical type of craniopharyngiomathird ventricle relationship.…”

Section: Discussionmentioning

confidence: 99%