Intraventricular choroid plexus tumors: clinical characteristics and impact of current management on survival

A rare trifocal presentation of a choroid plexus papilloma: Case report and review of the literature

“…Previously, it was thought that these tumors were most commonly seen in the pediatric population of which 70% of cases have been identified in patients under the age of two years old ( Anh Tuan et al, 2021 ; Browne-Farmer et al, 2021 ). However, based on the National Cancer Database of the American Cancer Society (NCBD), 54% of choroid plexus tumors (CPT) were detected in patients older than eighteen years of age, of which CPP's were more commonly encountered in the adult population, while atypical CPP's (aCPP) and choroid plexus carcinoma's (CPC) were more commonly encountered in the pediatric population ( Ruiz-Garcia et al, 2020 ). The average annual incidence for all CPT's is as low as 0.3 out of 1.000.000 per year ( Ruiz-Garcia et al, 2020 ).…”

“…According to the fifth edition of the WHO classification of central nervous system tumors, CPT's can be categorized as grade one (CPP), grade two (atypical CPP) or grade three (CPC) ( Thomas et al, 2021 ; Turkoglu et al, 2014 ; Hosmann et al, 2019 ; Safaee et al, 2013 ). The later are most frequently encountered in the pediatric population ( Turkoglu et al, 2014 ; Hosmann et al, 2019 ; Ruiz-Garcia et al, 2020 ). Based on the NCBD database, 69.2% are CPP's, 16.9% are aCPP's and 13.9% are CPC's ( Ruiz-Garcia et al, 2020 ).…”

“…The later are most frequently encountered in the pediatric population ( Turkoglu et al, 2014 ; Hosmann et al, 2019 ; Ruiz-Garcia et al, 2020 ). Based on the NCBD database, 69.2% are CPP's, 16.9% are aCPP's and 13.9% are CPC's ( Ruiz-Garcia et al, 2020 ). There is an equal distribution between males and females, although there is a male predominance in aCPP and CPC ( Ruiz-Garcia et al, 2020 ).…”

“…Based on the NCBD database, 69.2% are CPP's, 16.9% are aCPP's and 13.9% are CPC's ( Ruiz-Garcia et al, 2020 ). There is an equal distribution between males and females, although there is a male predominance in aCPP and CPC ( Ruiz-Garcia et al, 2020 ).…”

“…In a retrospective study of nine patients, GTR was achieved in 73% of patients, while another study of 36 patients mentioned a GTR rate of 92% ( Turkoglu et al, 2014 ; Hosmann et al, 2019 ). The NCDB database describes a GTR rate of 52% ( Ruiz-Garcia et al, 2020 ). Due to a young patient population and the risks of long-term neurological sequelae, it is of paramount importance to identify those patients that could benefit from adjuvant chemo- or radiotherapy ( Browne-Farmer et al, 2021 ).…”