Intravenous pyogenic granuloma

Abstract

A 43‐year‐old man presented with a 1‐month history of a nodule on the left side of the neck. There were no subjective symptoms. He denied any history of trauma. On physical examination, a round, soft, and movable subcutaneous nodule, approximately 1 cm in size, was detected. The overlying skin was normal. The nodule was observed to be attached to the wall of the external jugular vein during biopsy. On histopathologic examination, attachment to the external jugular vein was noted to be via a fibrovascular stalk ( Fig. 1a), and a lobular proliferation of capillaries, some of which were embedded in a fibromyxoid stroma, was observed ( Fig. 1b). There were no atypical cells, and a sparse inflammatory cell infiltrate was seen. The endothelial cells of the capillaries were CD31 positive ( Fig. 1c). 1 (a) Nodule attached to the wall of the vein (hematoxylin and eosin, × 10). (b) A lobular proliferation of capillaries, some of which are embedded in a fibromyxoid stroma (hematoxylin and eosin, × 40). (c) CD31 positivity (× 200)

Intravenous lobular capillary hemangioma originating in the iliac veins: A case report

“…1 Most patients are asymptomatic, but those that are symptomatic present with extremity edema or a painless mass. 1,6,10 There are no known associated risk factors; however, some reports suggest these lesions are linked with arteriovenous malformations. [11][12][13] The differential diagnosis characteristically focuses on vascular related pathologies, including deep venous thrombosis, aneurysm, ganglion or other neural lesion, vascular tumor, and papillary endothelial hyperplasia.…”

Intraluminal Pyogenic Granuloma of the Basilic Vein

“…2 In malignant tumors, we would anticipate marked involvement of venous walls and the surrounding soft tissues, as described by Rulli et al 6 The absence of extravenous extension and the preservation of venous wall integrity enabled us to practically exclude the possibility of a malignant venous tumor. The appearance of arterial flow of low resistance inside the venous thrombus excluded the possibility of an organized blunt thrombus.…”

“…1 Because of its characteristic histopathologic appearance, consisting of abundant capillaries growing in sparsely cellular, edematous, collagenous stroma, which may contain inflammatory cells, many authors prefer the name lobular capillary hemangioma. 1,3 Rarely, these benign lesions may occur intravenously, usually affecting veins of the neck and upper extremities [2][3][4] and occasionally veins of the ocular adnexa. 5 Histologically, intravenous PG appears as a single polypoid mass that is attached to the luminal surface of the vein wall through a fibrovascular stalk 2,3 or a broad base.…”

Intravenous pyogenic granuloma of the finger

“…Ghekiere et al noted that the history and physical fi ndings were similar in all patients with a usually asymptomatic mass. 4,[9][10][11] Pathologically, IVPG should be differentiated from other intravascular lesions including thrombus, intravascular papillary endothelial hyperplasia (IPEH), intravenous atypical vascular proliferation (IAVP), angiosarcoma, angiolymphoid hyperplasia with eosinophilia and histiocytoid hemangiomas. 7,9 We report these two cases because there are no reports on imaging diagnosis of IVPG of the fi nger; moreover, these two cases had similar locations in the fi ngers and identical MRI fi ndings.…”

“…[4][5][6][7][8] The clinical features are not characteristic enough to suggest the diagnosis. 4,9,10 The treatment of choice is complete local excision. The prognosis is excellent.…”