Intravenous nicardipine in severe systemic hypertension

Clifton, Gil; Cook, M. Eileen; Bienvenu, Gregory S.; Wallin, J. D.

doi:10.1016/0002-9149(89)90975-2

Cited by 15 publications

(4 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Intravenous nicardipine has been shown to decrease arterial BP acutely in non-pregnant subjects, when given either by bolus [3] or by continuous infusion [4,5]. Intravenous nicardipine has been shown to decrease arterial BP acutely in non-pregnant subjects, when given either by bolus [3] or by continuous infusion [4,5].…”

Section: Discussionmentioning

confidence: 99%

Intravenous nicardipine for severe hypertension in pre-eclampsia - effects of an acute treatment on mother and foetus

Aya¹,

Mangin²,

Hoffet

et al. 1999

Intensive Care Medicine

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Intravenous nicardipine for severe hypertension in pre-eclampsia - effects of an acute treatment on mother and foetus

Aya¹,

Mangin²,

Hoffet

et al. 1999

Intensive Care Medicine

View full text Add to dashboard Cite

show abstract

“…Several studies have investigated the role of nicardipine when administered to patients with severe hypertension (85,86). In two multicenter, prospective randomized trials comparing nicardipine with nitroprusside in patients with severe postoperative hypertension, Halpern et al and Neuteal et al reported that nicardipine is as effective as nitroprusside (87,88).…”

Section: Pharmacologic Agents Available For Treatment Of Hypertensivementioning

confidence: 99%

CRITICAL CARE ISSUES FOR THE NEPHROLOGIST: Current Diagnosis and Management of Hypertensive Emergency

Haas

Marik

2006

Seminars in Dialysis

View full text Add to dashboard Cite

The appropriate and timely evaluation and treatment of patients with severely elevated blood pressure is essential to avoid serious adverse outcomes. Most importantly, the distinction between a hypertensive emergency (crisis) and urgency needs to be made. A sudden elevation in systolic (SBP) and/or diastolic blood pressure (DBP) that is associated with acute end organ damage (cardiovascular, cerebrovascular, or renal) is defined as a hypertensive crisis or emergency. In contrast, acute elevation in SBP and/or DBP not associated with evidence of end organ damage is defined as hypertensive urgency. In patients with a hypertensive emergency, blood pressure control should be attained as expeditiously as possible with parenteral medications to prevent ongoing and potentially permanent end organ damage. In contrast, with hypertensive urgency, blood pressure control can be achieved with the use of oral medications within 24-48 hours. This paper reviews the management of hypertensive emergencies.

show abstract

“…Nicardipinc and isradipine. Some of the newer calciumchannel blockers have been studied for the treatment of hypertensive crises (89, 91, [103][104][105]. Sublingual nicardipine, a second-generation calcium-channel b l d e r similar to nifedipine, was compared with nifedipine in patients with hypertensive urgencies (91).…”

Section: Calcium-channel Blockersmentioning

confidence: 99%

“…Nicardipine and isradipine are not yet approved in the U.S.A. for the treatment of hypertensive crises. Based on the results from 66 patients, intravenous nicardipine appears to be a useful and safe agent for the management of this condition (105). Further study will be needed to determine the utility of orally and sublingually administered nicardipine and isradipine.…”

Section: Calcium-channel Blockersmentioning

confidence: 99%

Advances in pharmacotherapy: Treatment of hypertensive crisis

McKindley

Boucher

1994

J Clin Pharm Ther

View full text Add to dashboard Cite

SUMMARYA hypertensive crisis can be caused by many factors. Frequently, the mechanism involved is complex and highly variable among patients. Without drug therapy, this condition is associated with very high mortality and morbidity. There are a number of oral and intravenous hypotensive agents available, which can eff edively control blood pressure in a hypertensive crisis. The relative advantages and disadvantages of each treatment option is discussed.

show abstract

Intravenous nicardipine in severe systemic hypertension

Cited by 15 publications

References 16 publications

Intravenous nicardipine for severe hypertension in pre-eclampsia - effects of an acute treatment on mother and foetus

Intravenous nicardipine for severe hypertension in pre-eclampsia - effects of an acute treatment on mother and foetus

CRITICAL CARE ISSUES FOR THE NEPHROLOGIST: Current Diagnosis and Management of Hypertensive Emergency

Advances in pharmacotherapy: Treatment of hypertensive crisis

Contact Info

Product

Resources

About