Intravenous Magnesium Sulphate (MgSO4) for Postoperative Analgesia in Patients Undergoing Hip Surgeries Under Spinal Anaesthesia

A Single-center, Randomized, Clinical Trial of Opioid-free Analgesia Versus Routine Opioid-Based Analgesia Regimen for the Management of Acute Postoperative Pain Following Cesarean Section

“…This is in keeping with findings from previous studies that reported perioperative use of MgSO 4 with insignificant or no side effects at all. 7,12,18,19 There was no significant difference in Apgar scores at 5 minutes of neonates born to women in both arms of the study. This is in keeping with the finding of Helmy et al, suggesting therefore that perioperative MgSO 4 administration does not affect the status of the neonate at birth.…”

“…18 Akinyele also used bolus 30 mg/kg and continuous infusion (10 mg/kg/hr) and concluded that intravenous MgSO 4 as adjuvant analgesic under subarachnoid block improved postoperative analgesia and reduced postoperative opioid consumption with no side effects. 19 Apan et al administered bolus 5 mg/kg and 500 mg/hr infusion for 24 hours and pain scores were assessed 4-hourly in the 24 hours post-operation. 20 Pain scores were found to be similar in the magnesium and control groups except at 12 hours post-operation, showing unsustained pain control.…”