2013
DOI: 10.1016/j.tacc.2013.04.001
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Intravenous lipid emulsion therapy – The fat of the land

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Cited by 9 publications
(3 citation statements)
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“…With further research, lipid emulsions have also been found to be effective in the treatment of toxicity caused by lipid-soluble drugs. In 1962, Enhanced recovery from barbiturate-induced neurological depression in rats was demonstrated [5]. This was the first successful case of lipid emulsions counteracting drug toxidrome.…”
Section: Introductionmentioning
confidence: 98%
“…With further research, lipid emulsions have also been found to be effective in the treatment of toxicity caused by lipid-soluble drugs. In 1962, Enhanced recovery from barbiturate-induced neurological depression in rats was demonstrated [5]. This was the first successful case of lipid emulsions counteracting drug toxidrome.…”
Section: Introductionmentioning
confidence: 98%
“…There are two theories about the mechanism of action of IFE in case of local anesthetics -'lipid sink' theory and 'lipid flux' theory [5]. The lipid sink theory is more acceptable to describe the effect of IFE in cases of lipophilic drugs, since it could be explained as a kind of extraction of the drug from the blood and tissues expanding the lipid compartment [2,5].…”
Section: Introductionmentioning
confidence: 99%
“…The lipid sink theory is more acceptable to describe the effect of IFE in cases of lipophilic drugs, since it could be explained as a kind of extraction of the drug from the blood and tissues expanding the lipid compartment [2,5].…”
Section: Introductionmentioning
confidence: 99%