Intravenous lignocaine infusion facilitates acute rehabilitation after laparoscopic colectomy in the Chinese patients

Lee, Matthew Wh; Or, Debriel Yl; Tsang, Alex Cf; Ng, Dennis Ck; Pp, Chen; Cheung, Michael Hy; Li, Raymond Sk; Leong, HT

doi:10.12809/hkmj164984

Cited by 4 publications

(3 citation statements)

References 14 publications

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“… 6 The analgesic mechanisms are multifactorial, including sodium channel blockade, reduction in spinal cord sensitivity, synergistic effects with the GA agents and intrinsic systemic anti-inflammatory properties. 7 , 8 The analgesic efficacy of intravenous lidocaine has been observed mainly in abdominal surgeries, including colectomy, 9 gastrectomy, 10 and cholecystectomy. 11 Moreover, Kim et al confirmed the postoperative analgesic effects of intravenous lidocaine after ESD, 5 an endoscopic surgical procedure with natural lumens similar to operative hysteroscopy.…”

Section: Discussionmentioning

confidence: 99%

Effect of intravenous lidocaine on short-term pain after hysteroscopy: a randomized clinical trial

Peng

Zhao

Xiao

et al. 2021

Brazilian Journal of Anesthesiology (English Edition)

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Section: Discussionmentioning

confidence: 99%

Effect of intravenous lidocaine on short-term pain after hysteroscopy: a randomized clinical trial

Peng

Zhao

Xiao

et al. 2021

Brazilian Journal of Anesthesiology (English Edition)

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“…The analgesic mechanisms are multifactorial, including sodium channel blockade, reduction in spinal cord sensitivity and synergic effects with the general anesthetic agents [7]. The analgesic efficacy of intravenous lidocaine has been observed mainly in abdominal surgeries, including colectomy [8], gastrectomy [9], and cholecystectomy [10]. Moreover, Kim et al confirmed the postoperative analgesic effects of intravenous lidocaine after ESD [5], an endoscopic surgical procedure of natural lumens similar to operative hysteroscopy.…”

Section: Discussionmentioning

confidence: 99%

Application of intravenous lidocaine in patients undergoing operative hysteroscopy: a randomized, double-blind, controlled study

Wang

Peng

Xiao

et al. 2019

Preprint

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Background The role of intraoperative intravenous lidocaine infusion has been previously evaluated for pain relief, inflammatory response, and post-operative recovery, including in endoscopic surgery. The present study is a randomized double-blinded trial in which we evaluated whether intravenous lidocaine infusion would reduce postoperative pain, propofol requirement and remifentanil consumption in patients undergoing hysteroscopy surgery. Methods Eighty-five patients scheduled to undergo elective operative hysteroscopy surgery under general anesthesia were randomized into two groups. Group L included patients who received an intravenous lidocaine bolus 1.5mg/kg over 3 min followed by a continuous infusion at the rate of 2 mg/kg/h until surgery completed, and Group C received 0.9% normal saline solution at an equivalent rate. The depth of anesthesia was monitored using the Narcotrend, which was based on measurement of the patient’s cerebral electrical activity. Primary outcome of the study was postoperative hypogastric pain evaluating by visual analogue scale (VAS). Secondary outcomes include propofol requirement and remifentanil requirement. Results VAS score of Group L was significantly lower than Group C at postoperative 0.5 h, 4 h, respectively (P < 0.05), while no obvious difference was found at postoperative 24 h. There was no difference between groups in propofol requirement, but Group L required less dosage of remifentanil than Group C (P < 0.05). Moreover, the incidence of throat pain was significantly lower in Group L. No adverse events associated with lidocaine was discovered. Conclusions Administration of intravenous lidocaine infusion as an adjuvant alleviated short-term postoperative hypogastric pain and throat pain, and reduced remifentanil requirement in patients undergoing operative hysteroscopy surgery.

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“…In addition to the analgesic and anti-hyperalgesic properties in acute and neuropathic pain syndromes, by modifying the secretion of specific cytokines, lidocaine decreases the systemic inflammatory response (11,12). Furthermore, the appeal of lidocaine as an adjunct in the ERAS protocols has been reinforced by the validation of its safety profile through various animal and clinical studies (11)(12)(13)(14)(15).…”

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confidence: 99%

Efficacy of Intravenous Use of Lidocaine in Postoperative Pain Management After Laparoscopic Colorectal Surgery: A Meta-analysis and Meta-regression of RCTs

Sarakatsianou

Perivoliotis

Tzovaras

et al. 2021

In Vivo

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Background/Aim: Current literature reports regarding the effect of lidocaine in laparoscopic colectomies are still inconclusive. The purpose of this study was to review the current literature and estimate the overall effect of intravenous lidocaine administration in postoperative recovery of patients submitted to laparoscopic colectomies. Materials and Methods: This study was completed based on the PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. A systematic screening using scholar databases was performed (Medline, Scopus, Web of Science, CENTRAL). Results: In total, 8 studies and 407 patients were included in this meta-analysis. Introduction of intravenous lidocaine in the perioperative analgesia scheme did not improve hospitalization duration (p=0.23), morphine consumption (p=0.96), perioperative bowel function (first flatus p=0.40, first bowel opened p=0.13, first diet p=0.16), or the overall complication rates (p=0.42). Overall, high heterogeneity levels were identified. Conclusion: Current evidence indicates that lidocaine does not improve rehabilitation after laparoscopic colectomies.

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Intravenous lignocaine infusion facilitates acute rehabilitation after laparoscopic colectomy in the Chinese patients

Cited by 4 publications

References 14 publications

Effect of intravenous lidocaine on short-term pain after hysteroscopy: a randomized clinical trial

Effect of intravenous lidocaine on short-term pain after hysteroscopy: a randomized clinical trial

Application of intravenous lidocaine in patients undergoing operative hysteroscopy: a randomized, double-blind, controlled study

Efficacy of Intravenous Use of Lidocaine in Postoperative Pain Management After Laparoscopic Colorectal Surgery: A Meta-analysis and Meta-regression of RCTs

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