kept under 21 cm. The tubing connected with the cannula in the left ureter was then clamped. The femoral vein was iso¬ lated, and from 100 to ISO c.c. of a S per cent, sodium sulphate solution were injected slowly. The secretory pressure of the right kidney was measured in the graduated tube connected with the right ureter. After from two to three hours the routine procedure as previously described was carried out. The organisms were introduced under a very low pressure and the intrapelvic pressure was subsequently increased by stimulation of the kidney. The results are shown in Table 3. In four of these five experiments, Bacillus prodigiosus was recovered in other organs than the kidney.It may be concluded, therefore, that bacteria can pass from the kidney pelvis into the blood stream, and that they may do this under conditions analogous to some of the pathologic states found in man.One of the trying experiences of the medical profession during the late pandemic of influenza was the apparent helplessness in the treatment of the chief complication, pneumonia. The experience at the Camp Travis Base Hospital probably paralleled that of other similar institutions. At first, only the commonly accepted methods of treatment were used; but it soon became evident that some additional measures must be employed, else a very high mortality would result. At this hospital, resort was made to the use of quinin because of its recognized pneumococcidal action, and to the intravenous injections of hypertonic glucose solution. The results following the quinin medication are to be reported by others. The good results following the glucose treatment are attested by a relatively low mortality. This report deals with the results obtained in 319 cases of influenzal pneumonia, in which one or more injections of a sterile hypertonic glucose solution were used.The use of glucose in the treatment of serious diseases is not new : heretofore, its use has been restricted chiefly to administration by mouth and rectum for the purpose of supplying the organism with a food easily assimilated and of high caloric value. Litchfield1 has recently urged the intravenous use of hypertonic glu¬ cose solution in serious diseases. The present report is offered because it comprises the largest series of cases on record in which the intravenous use of a hypertonic glucose solution has been intensively employed in the treatment of pneumonia.
PREPARATION OF SOLUTION AND TECHNIC OF
INJECTIONThe solutions were prepared in the base hos¬ pital laboratory from chemically pure glucose : Several thousand cubic centimeters of a solution of a desired strength were prepared in distilled water brought 1. Litchfield. Lawrence: Glucose Intravenously as a Therapeutic Measure, J. A. M. A. 71:503 (Aug. 17) 1918.slowly to the boiling point in order to dissolve the glucose, and filtered through a heavy layer of cotton to remove any gross contamination ; then they were made up to the original volume, autoclaved at 20 pounds pressure for twenty minutes, again filtered through sev...
