Intravenous heparin in combination with antibiotics for the treatment of deep vein septic thrombophlebitis: A systematic review

Falagas, Matthew E.; Vardakas, Konstantinos Z.; Athanasiou, Stavros

doi:10.1016/j.ejphar.2006.11.068

Cited by 49 publications

(44 citation statements)

References 27 publications

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“…There is a lack of comparative trials studying the effectiveness and toxicity of heparin in patients with septic thrombosis [40][41][42]. In our study, none of the sinus thrombosis was cured with heparin treatment.…”

Section: Minor Issues Of the Studymentioning

confidence: 96%

Acute mastoiditis in children: A retrospective study of 188 patients

Quesnel

Nguyen

Pierrot

et al. 2010

International Journal of Pediatric Otorhinolaryngology

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Section: Minor Issues Of the Studymentioning

confidence: 96%

Acute mastoiditis in children: A retrospective study of 188 patients

Quesnel

Nguyen

Pierrot

et al. 2010

International Journal of Pediatric Otorhinolaryngology

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“…A systematic review of the use of i.v. heparin for the treatment of all forms of septic thrombophlebitis concluded that heparin was a useful addition to the antimicrobial treatment regimen and that the risk of complications from anticoagulation therapy is low (826). Thus, guidelines for the management of CLABSI suggest that anticoagulation therapy with heparin should be considered for the treatment of individuals with septic thrombophlebitis (647).…”

Section: Septic Thrombophlebitismentioning

confidence: 99%

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

et al. 2015

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SUMMARY Staphylococcus aureus is a major human pathogen that causes a wide range of clinical infections. It is a leading cause of bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device-related infections. This review comprehensively covers the epidemiology, pathophysiology, clinical manifestations, and management of each of these clinical entities. The past 2 decades have witnessed two clear shifts in the epidemiology of S. aureus infections: first, a growing number of health care-associated infections, particularly seen in infective endocarditis and prosthetic device infections, and second, an epidemic of community-associated skin and soft tissue infections driven by strains with certain virulence factors and resistance to β-lactam antibiotics. In reviewing the literature to support management strategies for these clinical manifestations, we also highlight the paucity of high-quality evidence for many key clinical questions.

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“…25 The only randomized trial showed no benefit with the addition of heparin, and a systematic review concluded that heparin use in SPT remains controversial as there is no conclusive evidence that it provides benefit above and beyond adequate antimicrobial therapy. 25,27 See Table 1 for therapy recommendations.…”

Section: Septic Pelvic Thrombophlebitismentioning

confidence: 99%

Post partum infections: A review for the non-OBGYN

Dalton

Castillo

2014

Obstet Med

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The epidemiology of infections in the puerperium (post partum period) is not well understood and remains underestimated because surveillance systems are often limited to the acute care setting. The most common source of persistent fever after delivery is genital tract infection for which diagnosis remains mostly clinical and antibiotic treatment empiric. This review will emphasize surgical site infections (SSIs) and endometritis. Septic thrombo-phlebitis, mastitis, urinary tract infections and rare infections will be covered in less detail. Puerperal sepsis will not be reviewed.

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Intravenous heparin in combination with antibiotics for the treatment of deep vein septic thrombophlebitis: A systematic review

Cited by 49 publications

References 27 publications

Acute mastoiditis in children: A retrospective study of 188 patients

Acute mastoiditis in children: A retrospective study of 188 patients

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

Post partum infections: A review for the non-OBGYN

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