Intravenous Application of Pulsed Radiofrequency–4 Case Reports

Teixeira, A.; Sluijter, Menno E.

doi:10.5812/aapm.10242

Cited by 6 publications

(8 citation statements)

References 16 publications

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“…The duration of pain relief was much longer than would have been expected from steroid injections according to the literature. We therefore recommend that further research comparing the effects of this method to a control series be undertaken.We have postulated that the effect of intra-articular PRF is caused by the exposure of immune cells to low-strength RF fields ( 31 , 32 ). We recommend that PRF not be combined with steroid infiltration until the exact nature of this mechanism has been clarified.…”

Section: Discussionmentioning

confidence: 99%

The Treatment of Joint Pain with Intra-articular Pulsed Radiofrequency

Schianchi¹,

Sluijter

Balogh

2013

Anesth Pain

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BackgroundThe intra-articular (IA) application of pulsed radiofrequency (PRF) for pain in small and large joints represents a recent development that has proven to be effective in many cases. We performed a retrospective study of 89 such procedures in 57 consecutive patients with chronic articular pain.ObjectivesThe aim of this retrospective study is to evaluate the effectiveness of intraarticular PRF in a group of 57 consecutive patients with chronic joint pain.Patients and MethodsPatients with intractable joint pain for more than 6 months were treated with IA PRF 40-45V for 10-15 min in small joints and 60V for 15 min in large joints using fluoroscopic confirmation of correct needle position. A total of 28 shoulders, 40 knees, 10 trapezio-metacarpal, and 11 first metatarso-phalangeal joints were treated. Results were evaluated at 1, 2, and 5 months. The procedure was repeated after 1 month in 10 patients with initial suboptimal results. Success was defined as a reduction of pain score by at least 50%.ResultsAll groups showed significant reductions in pain scores at all three follow-up visits. Success rates were higher in small joints (90% and 82%, respectively) than large ones (64% and 60%, respectively). Interestingly, IA PRF was successful in 6 out of 10 patients who had undergone previous surgery, including 3 with prosthetic joint replacement and in 6 of the 10 repeated procedures. There were no significant adverse effects or complications.ConclusionsIA PRF induced significant pain relief of long duration in a majority of our patients with joint pain. The exact mechanism is unclear, but may be related to the exposure of immune cells to low-strength RF fields, inducing an anti-inflammatory effect. The success rate appears to be highest in small joints. We recommend additional research including control groups to further investigate and clarify this method; our data suggest that it may represent a useful modality in the treatment of arthrogenic pain.

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Section: Discussionmentioning

confidence: 99%

The Treatment of Joint Pain with Intra-articular Pulsed Radiofrequency

Schianchi¹,

Sluijter

Balogh

2013

Anesth Pain

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“…The immune system came into focus, suggesting that PRF could possibly influence the nociceptive process itself. An initial report on a second invention by Teixeira is published in this issue ( 3 ). Its background follows from his invention of intra-articular PRF.…”

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confidence: 99%

Evolution and Mode of Action of Pulsed Radiofrequency

Sluijter

Imani

2013

Anesth Pain

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“…PRF is not limited to targeting afferent nerves, which was observed after the use of intra-articular PRF, and, as a result, it was verified that PRF promotes an analgesic effect. Therefore, it was suggested that PRF could present a local anti-inflammatory effect due to an effect on the immune system, which may ultimately impact the nociceptive process [ 22 , 23 ].…”

Section: Pulsed Radiofrequency: Mechanisms Of Actionmentioning

confidence: 99%

“…This may explain the mechanisms of long-term pain mitigation after using PRF [ 24 ]. Given its ability to impact immune cells, there are case reports considering the intravenous route to apply RF in order to treat unresolved immune issues [ 22 ].…”

Section: Pulsed Radiofrequency: Mechanisms Of Actionmentioning

confidence: 99%

The Mechanism of Action between Pulsed Radiofrequency and Orthobiologics: Is There a Synergistic Effect?

Jorge¹,

Huber²,

Rodrigues³

et al. 2022

IJMS

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Radiofrequency energy is a common treatment modality for chronic pain. While there are different forms of radiofrequency-based therapeutics, the common concept is the generation of an electromagnetic field in the applied area, that can result in neuromodulation (pulsed radiofrequency—PRF) or ablation. Our specific focus relates to PRF due to the possibility of modulation that is in accordance with the mechanisms of action of orthobiologics. The proposed mechanism of action of PRF pertaining to pain relief relies on a decrease in pro-inflammatory cytokines, an increase in cytosolic calcium concentration, a general effect on the immune system, and a reduction in the formation of free radical molecules. The primary known properties of orthobiologics constitute the release of growth factors, a stimulus for endogenous repair, analgesia, and improvement of the function of the injured area. In this review, we described the mechanism of action of both treatments and pertinent scientific references to the use of the combination of PRF and orthobiologics. Our hypothesis is a synergic effect with the combination of both techniques which could benefit patients and improve the life quality.

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Intravenous Application of Pulsed Radiofrequency–4 Case Reports

Cited by 6 publications

References 16 publications

The Treatment of Joint Pain with Intra-articular Pulsed Radiofrequency

The Treatment of Joint Pain with Intra-articular Pulsed Radiofrequency

Evolution and Mode of Action of Pulsed Radiofrequency

The Mechanism of Action between Pulsed Radiofrequency and Orthobiologics: Is There a Synergistic Effect?

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