Intravascular Papillary Endothelial Hyperplasia at Foot Level: A Case Report and Literature Review

An intravascular papillary endothelial hyperplasia of the hand radiologically mimicking a hemangiopericytoma: A case report and literature review

“…Clinically, IPEH presents as a palpable soft-tissue mass, often located within normal or dilated vascular spaces and characterized by slow growth. 2 An unusual case with rapid growth was recently reported by Corni et al, 9 but they did not observe recurrence or complications at 6 months follow-up. Furthermore, though in the recent literature 15% of recurrence rate was noted; 9 all these cases had a benign natural history.…”

“… 7 The most common locations are the hand fingers, followed by the head and neck, although a few cases have been identified at the foot district. 2 IPEH rarely develops intracranially, where it may present as mass lesion, thus mimicking a malignant neoplasia. 8 Intracranial IPEH could have a significant morbidity and should be considered in the differential diagnosis for mass lesions in patients that have undergone gamma knife radiosurgery.…”

“…Hashimoto et al 1 classified IPEH into three types: type I IPEH presents de novo, in normal blood vessels; type II IPEH can develop from a pre-existing vascular process, that is, a haemangioma, a pyogenic granuloma or a haematoma, while type III IPEH, which is the least common variant, has an extravascular location and generally arises from a post-traumatic haematoma. 2 , 3 …”

Masson’s Tumor of the Hand: An Uncommon Histopathological Entity

“…Pins et al described in their study a female to male ratio of 1.2 : 1.0 with an average age presentation of 34 years [10]. IPEH usually presents as a small, firm, superficial mass with slow growth [11,12]. It may occur in any part of the body but the most common locations are hands, fingers, head, and neck, respectively [11]; however, oral mucosa, lip, thyroid, maxillary sinus, parotid, lung, superior vena cava, adrenal gland, renal vein, forearm, foot, and the intracranium have also been reported [1,[13][14][15][16][17].…”

Intravascular Papillary Endothelial Hyperplasia – Case Report

“…Cases of IPEH located on the oral and lingual mucosa, in the gastrointestinal tract, liver, uterus, heart, intracranially, or in the orbital area have also been reported 10 . IPEH generally presents as a solitary well-circumscribed, round or ovoid, red or purple slow growing papule, nodule or soft-tissue mass, 0.2-5 cm in diameter 11 . Most lesions are asymptomatic, but some patients complain of local pain, especially when IPEH develops in a thrombosed varix 10 .…”