Intravascular Large B-cell Lymphoma within Duodenal Gastrointestinal Stromal Tumor

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare disease of intravascular growth of malignant lymphocytes without an obvious extravascular tumor mass or existence in peripheral blood. It has poor prognosis due to its aggressive behavior and rapid systemic dissemination. But there is no pathognomonic finding, diagnosis of IVLBCL is still challenging. Here we report a case of IVLBCL found within a resected specimen of duodenal gastrointestinal stromal tumor.

Intravascular Large B-Cell Lymphoma Within the Appendix Presenting as Acute Abdomen: A Challenging Diagnosis for Hematologists

“…Although rare cases of ILBCL of the gastrointestinal tract have been previously described [ 3 , 4 , 5 , 6 ], to our knowledge there have been no reports of ILCL of B-cell origin with appendix involvement in the English literature. The only reported case of ILCL involving the appendix was of T-cell origin, described by Malicki et al [ 7 ] in 1999.…”