Intravascular Hemolytic Syndrome Following Aortic Valve Replacement

Using serum haptoglobin concentration as an index, the frequency of hemolysis has been determined in 110 consecutive, non-selected patients with aortic valvular lesions admitted to Medical Department B, Rikshospitalet, during one year from February 1968.Marked lowering or absence of serum haptoglobin was seen in 11 of 65 patients with aortic valvular disease, hemolysis being about twice as frequent in aortic insufficiency as in aortic stenosis. Values indicating hemolysis were observed in 37 of 45 patients with a Starr-Edwards aortic ball-valve prosthesis. In most cases hemolysis was slight; no case with clinically important hemolytic anemia was seen. Marked lowering of the serum haptoglobin concentration seems to be the most sensitive qualitative indicator of hemolysis, the serum lactic dehydrogenase activity probably giving additional information about the rate of hemolysis. 1.2.

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Intravascular Hemolytic Syndrome Following Aortic Valve Replacement

Cited by 6 publications

References 14 publications

Traumatic Hemolysis With Rupture of Aneurysm of Sinus of Valsalva

Traumatic Hemolysis With Rupture of Aneurysm of Sinus of Valsalva

The Management of Patients with Prosthetic Heart Valves

Mechanical Hemolysis in Aortic Valvular Disease and Aortic Ball‐valve Prosthesis

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