Intravascular Hemolysis in Aluminium Phosphide Poisoning

Abstract

Hemolysis associated with aluminum phosphide poisoning is very rare. Intravascular hemolysis in presence of glucose-6-phosphate dehydrogenase (G6PD) deficiency has been reported rarely in literature. We are reporting a case of young male patient with history of aluminum phosphide poisoning and complicated with intravascular hemolysis without G6PD deficiency. It has been reported only once in the literature. How to cite this article Malakar S, Dass B et al . Intravascular Hemolysis in Aluminum Phosphide Poisoning. Indian J of Crit Care Med 2019;23(2):106-107.

Inhalational Wheat-pill Poisoning: A Household Chemical Warfare Agent

“…The main target seems to be the cardiovascular system so much so that, sometimes, the poisoning can be confused with a cardiac ischemic event [6]. A rare complication has been described as intravascular hemolysis [7].…”

Osmotic fragility duringin vitroerythrocyte cytotoxicity induced by aluminium chloride, lead acetate or mercuric chloride in hyposmolar sucrose media

“…Anemia is an important toxic effect arising from their toxicosis (Flora et al ., 2012; Wani et al ., 2015; Igbokwe et al ., 2019; Vianna et al ., 2019). Haemolytic anemia has been reported in intoxications with aluminium (Aggarwal et al ., 1999; Soltaninejad et al ., 2011; Arefi et al ., 2013; Malakar et al ., 2019), lead (Warang et al ., 2017) and mercury (Ribarov et al ., 1983; Maheswaram et al ., 2008; Yildirim et al ., 2012; Ekawanti et al ., 2015; Weinhouse et al ., 2017). The anemia is caused when the metallic ions induce membrane damage which predisposes the erythrocytes to intravascular hemolysis or removal from the bloodstream by phagocytes in the reticuloendothelial organs.…”