Intrauterine Insemination: Fundamentals Revisited

Allahbadia, Gautam N.

doi:10.1007/s13224-017-1060-x

Cited by 33 publications

(19 citation statements)

References 47 publications

(75 reference statements)

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“…Though the technique has essentially remained the same, several advances in the stimulation protocols, gonadotropins, sperm preparation techniques and ultrasound monitoring have led to promising success rates with IUI. 17 Changes in the frequency and the time of IUI are mentioned as significant factors to improve the chance of fertility by IUI. 15,18 Combining COH with IUI was associated with better results than only COH in couples with unexplained infertility.…”

Section: Resultsmentioning

confidence: 99%

Does increasing the number of inseminations per cycle increase the probability of conception? a randomized trial comparing single versus double intrauterine insemination

Khandavalli

Rai

2020

Int J Reprod Contracept Obstet Gynecol

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Background: Intrauterine insemination (IUI) remains an inexpensive, non-invasive, and effective first-line artificial insemination technique. The technique of IUI has evolved through various innovations since the time Cohen published the first report of IUI in 1962, and the success rate increased from 5% to >20%. The success of IUI depends upon several factors; two such prognostic factors are the timing and frequency of insemination. The objective of this study was to compare the effectiveness of single versus double intrauterine insemination.Methods: This prospective randomized study was carried out in 130 patients with male factor infertility, PCOS and unexplained infertility. Patients were randomly assigned into two groups. In the first group of 65 patients, single IUI was applied at 36 to 40 hours after HCG administration, to the other 65 patients in the second group, double IUIs were applied at 12 to 16 hours and 36 to 40 hours after HCG administration. The primary end-point of the study was to compare the clinical pregnancy rate between the two groups.Results: The overall pregnancy rate was 18.46% (12/65) for single IUI group and 30.76% (20/65) for double IUI group. There was a no statistically significant difference between single and double IUI groups (p=0.16).Conclusions: This study did find a higher pregnancy rate following double IUI; however, the difference was not statistically significant. Further, larger sample size studies are required to determine if double IUI increases the pregnancy rate.

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Section: Resultsmentioning

confidence: 99%

Does increasing the number of inseminations per cycle increase the probability of conception? a randomized trial comparing single versus double intrauterine insemination

Khandavalli

Rai

2020

Int J Reprod Contracept Obstet Gynecol

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“…The composition of seminal fluid from different men differs in makeup across a number of analytes [14]. While not completely understood, the reasons for these differences may be linked to differences in donor genetics, diet, and activity level prior to sample delivery [15,16]. Furthermore, discrepancies between samples provided by the same donor on a different day or time of day have been noted.…”

Section: Discussionmentioning

confidence: 99%

Relationship between Human Seminal Prostaglandins on Intrauterine Insemination Pregnancy Outcomes

EW¹,

RJ²,

Zimmerman³

et al. 2021

Gynecol Women’s Health Res

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“…Reviewing the IUI process, processed sperm are placed in the female uterus. 17 The process of pregnancy starts from the spermatozoa that meet the oocyte in the fallopian tube and fertilization occurs. Furthermore, the embryo in the fallopian tube moves with the help of smooth muscle movement of the cilia of the epithelium of the fallopian tube towards the uterus for implantation.…”

Section: Ibu General Hospital Denpasarmentioning

confidence: 99%

Relationship Between Smoker Male Partner and Intrauterine Insemination Success in Kasih Ibu General Hospital Denpasar

Salim

Kurniawan

Pramesemara

2021

IABJ

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Background : Assisted reproductive technology, one of which is intrauterine insemination (IUI) allows infertile couples to get pregnant. The pregnancy success of IUI procedure varies among individuals. Objective: The study aim is to determine whether there is a relationship between smoker male partners and IUI success. Methods: This research is an analytic study with cross-sectional approach conducted at Kasih Ibu General Hospital Denpasar with purposive sampling technique. There are 35 male couples aged 25-50 years who underwent the IUI procedure selected as samples. The research data was gathered from patient's medical records and statistically analyzed using the Chi-Square test. Results: The study found that of the 35 samples, 13 (37.1%) were smokers, whereas 22 (62.9%) male partners were non-smokers. There were 6 (17.1%) samples’ partners who were pregnant after undergoing the IUI procedure, and 29 (82.9%) samples’ partners were not pregnant. It was found that there was no significant relationship between male partner smokers and the success of IUI at Kasih Ibu General Hospital Denpasar (p=0.832). However, in descriptive analysis and relative risk calculation, smoker male partner is less likely to achieve pregnancy than non-smoker’s male partner (RR=0.85). Conclusion: Smoker male partners may not contribute to IUI success. Further studies should be done with a higher number of samples, multicenter, and more controlled risk factors to make it more accurate in determining the relationship.

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Intrauterine Insemination: Fundamentals Revisited

Abstract: Intrauterine insemination (IUI) is an assisted conception technique that involves the deposition of a processed semen sample in the upper uterine cavity, overcoming natural barriers to sperm ascent in the female reproductive tract. It is a cost-effective, noninvasive first-

Cited by 33 publications

References 47 publications

Does increasing the number of inseminations per cycle increase the probability of conception? a randomized trial comparing single versus double intrauterine insemination

Does increasing the number of inseminations per cycle increase the probability of conception? a randomized trial comparing single versus double intrauterine insemination

Relationship between Human Seminal Prostaglandins on Intrauterine Insemination Pregnancy Outcomes

Relationship Between Smoker Male Partner and Intrauterine Insemination Success in Kasih Ibu General Hospital Denpasar

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