Intratumoral Injection of Hypertonic Glucose in Treating Refractory Pneumothorax Caused by Microwave Ablation: a Preliminary Study

Wang, Dongdong; Li, Xiaoguang; Wang, Yu

doi:10.1007/s00270-019-02195-9

Cited by 4 publications

(2 citation statements)

References 15 publications

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“…Patients with pneumonia and lung abscess showed a good response to sputum culture-specific antibiotics and were discharged within 2 weeks. The two refractory pneumothorax patients showed no evidence of bronchopleural fistula, and were effectively managed by combined intratumoral injection of hypertonic glucose and continuous catheter drainage, which has been described in our previous publication [18]. The two patients were discharged after 20-and 30-day hospital stays, respectively, without recurrence of pneumothorax during follow-up.…”

Section: Safetymentioning

confidence: 68%

Microwave ablation of lung malignancies with coexisting severe emphysema: a retrospective analysis of safety and efficacy in 26 patients

Peng

Bie

et al. 2021

International Journal of Hyperthermia

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Purpose: This retrospective study aimed to evaluate the safety and efficacy of microwave ablation (MWA) for lung malignancies in patients with severe emphysema. Materials and methods: The clinical records of 1075 consecutive patients treated for malignant lung tumors in our department were retrospectively reviewed. Emphysema was assessed based on standard-dose computed tomography (CT) and was considered severe when it occupied !25% of the lung. Overall, 26 patients (24 men and 2 women; mean age ± standard deviation [SD]: 71.23 ± 8.18 years, range: 59-88 years) with severe emphysema underwent CT-guided percutaneous MWA for treating 26 tumors (24: non-small cell lung cancer and 2: metastases). The mean tumor size was 3.0 cm (SD: 1.5, range: 1.2-6.5 cm). Follow-up was performed with CT at 1, 3, 6, 12 months after ablation, and every 6 months thereafter. Complications and efficacy were evaluated. Results: The median follow-up duration in all patients was 17.5 months (range: 5-37 months, interquartile range: 15.8). The mortality rate was 0% within 30 days after ablation. Major complications including pneumonia, lung abscess and refractory pneumothorax occurred in 19.2% (5/26) patients. The technical success and efficacy rates were 88.5% (23/26) and 87.0% (20/23), respectively, and the local tumor progression rate was 30.0% (6/20). Conclusion: MWA appears to be a safe and effective therapeutic option for treating lung malignancies in patients with severe emphysema.

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Section: Safetymentioning

confidence: 68%

Microwave ablation of lung malignancies with coexisting severe emphysema: a retrospective analysis of safety and efficacy in 26 patients

Peng

Bie

et al. 2021

International Journal of Hyperthermia

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“…Most pneumothorax cases are self‐limiting and can be treated conservatively, whereas 10% of the cases require chest tube drainage 55 . The combined method of intratumoral injection of hypertonic glucose and continuous catheter drainage under low negative pressure may be an effective method to treat refractory pneumothorax caused by MWA 56 . In addition, patients should be monitored for delayed pneumothorax (72 hours after ablation) 57 …”

Section: Complicationsmentioning

confidence: 99%

Image‐guided percutaneous microwave ablation of early‐stage non–small cell lung cancer

2020

Asia-Pac J Clncl Oncology

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Although surgical lobectomy with systematic mediastinal lymph node evaluation is considered as the "gold standard" for management of early stage non-small cell lung cancer (NSCLC), image-guided percutaneous thermal ablation has been increasingly used for medically inoperable patients. Radiofrequency ablation (RFA) is a researchbased technique that has the most studies for medically inoperable early-stage NSCLC. Other thermal ablation techniques used to treat pulmonary tumors include microwave ablation (MWA), cryoablation and laser ablation. MWA has several advantages over RFA including reduced procedural time, reduced heat-sink effect, large ablation zones, decreased susceptibility to tissue impedance, and simultaneous use of multiple antennae. This review article highlights the most relevant updates of MWA for the treatment of early-stage NSCLC, including mechanism of action, clinical outcomes, potential complications, the existing technique problems and future directions.

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Magnetic Iron Oxide Nanoparticles via Intratumoral Injection for Cancer Photothermal Therapy

Chu

2024

Laser-Triggered Nanobiomaterials for Inhibiting Tumor Growth

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Intratumoral Injection of Hypertonic Glucose in Treating Refractory Pneumothorax Caused by Microwave Ablation: a Preliminary Study

Cited by 4 publications

References 15 publications

Microwave ablation of lung malignancies with coexisting severe emphysema: a retrospective analysis of safety and efficacy in 26 patients

Microwave ablation of lung malignancies with coexisting severe emphysema: a retrospective analysis of safety and efficacy in 26 patients

Image‐guided percutaneous microwave ablation of early‐stage non–small cell lung cancer

Magnetic Iron Oxide Nanoparticles via Intratumoral Injection for Cancer Photothermal Therapy

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