Intrathecal Baclofen Infusion Pumps in the Treatment of Spasticity: A Retrospective Cohort Study in a Portuguese Centre

Reis, Pedro; Vieira, Catarina Rocha; Midões, Ana Cristina; Rebelo, Virgínia; Barbosa, Patrícia; Gomes, A.

doi:10.20344/amp.10482

Cited by 17 publications

(5 citation statements)

References 27 publications

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“…[ 50 , 51 ] This is an attractive approach for improving spasticity in children with CP because it enables less invasive treatments. In addition, alternative treatment explored in the literature include intrathecal baclofen), [ 52 ] selective dorsal rhizotomy (intrathecal baclofen therapy is not available), [ 53 ] and extracorporeal shockwave therapy has been applied to the treatment of spasticity. [ 54 ] There are some limitations, however, it is still evaluating the effectiveness and reliability of these therapies by RCT.…”

Section: Resultsmentioning

confidence: 99%

Treatment on patients with spastic cerebral palsy in the past 30 years: A systematic review and bibliometric analysis

Chen

et al. 2022

Medicine

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Background: Over the past 30 years, treatments from different disciplines have been applied to spastic cerebral palsy (SCP). However, few bibliometric studies have been conducted to date. This study explored the knowledge base, emerging hotspots, and future trends related to SCP treatment research using bibliometric analysis.Methods: Publications on SCP treatment included in the Web of Science Core Collection database between 1990 and 2020 were retrieved, and Medical Subject Headings terms were extracted from PubMed. Online bibliometric analysis website (http:// bibliometric.com/), 2 pieces of software called "CiteSpace" and "VOSViewer" were used for quantitative analysis and knowledge map establishment.Results: A total of 1668 papers were retrieved from 1990 to 2020. The number of publications has increased annually. Developmental Medicine and Child Neurology is the most productive and the highest co-cited journal. The United States has been the largest contributor. Vrije Universiteit Amsterdam ranked first in the number of papers published among institutions that have conducted correlational research. Becher JG and Graham HK should be considered scholars who have made outstanding contributions. The knowledge base of the SCP treatment research field is thoughtfully constructed to promote understanding of the field.Conclusion: This bibliometric study identified global achievements, research hotspots, and trends of SCP treatment. They provide insights into the research field and valuable information for future scientific research and clinical treatment.

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Section: Resultsmentioning

confidence: 99%

Treatment on patients with spastic cerebral palsy in the past 30 years: A systematic review and bibliometric analysis

Chen

et al. 2022

Medicine

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“…Pump displacement and exposure comprise 7% of all complications in one retrospective review of 251 implantable pump placements. 1 In addition to patient discomfort from pump rotation within the abdominal pocket, frequent rotation and displacement contribute to catheter kinking and eventual obstruction. 11 Similarly, pump rotation poses a significant challenge for the clinician tasked to refill the pumps in the outpatient setting.…”

Section: Discussionmentioning

confidence: 99%

“…This study was approved by the Houston Methodist Research Institute Institutional Review Board (PRO00034658). 1…”

Section: Acknowledgmentsmentioning

confidence: 99%

“…T he first intrathecal drug pump (ITDP) was developed in 1981 and has since become a widely used treatment modality. 1 Modern ITDPs consist of a subcutaneous pump and an extension catheter placed intrathecally to deliver drugs directly to spinal fluid. 2,3 ITDPs have a therapeutic advantage compared with oral or intravenous (IV) medications because drugs can be delivered in smaller quantities, bypass systemic circulation, decrease systemic toxicity, and increase bioavailability to the therapeutic target.…”

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confidence: 99%

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Treatment of Intrathecal Drug Pump Flipping Using Fascial Flaps: A Technical Description and Case Series

Taghlabi,

Bhenderu,

Guerrero

et al. 2023

Operative Neurosurgery

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BACKGROUND AND OBJECTIVES: Intrathecal drug therapy is a common treatment for dystonia, pain, and spasticity using implanted pump and catheter systems. Standardized management of intrathecal drug pump (ITDP) migration and flipping has not been well established in the literature. This study reports the use of soft tissue to address less common pump complications such as pump flipping, migration, and difficulty in medication refill. METHODS: A retrospective chart review of intrathecal pump cases performed by two surgeons between February 2020 and August 2022 was conducted. Patients with complications such as pump flipping, migration, or challenges in medication refill treated with soft tissue flaps were included. Patient demographics, comorbidities, and perioperative data were collected. RESULTS: A total of five patients with ITDP complicated by pump flipping, migration, malposition, or difficulty in medication refill that were treated using fascial flaps were included in the study. Three technical considerations when revising ITDP complications are secure pump anchoring, reliable wound closure, and ease of pump medication refill. Cases 1 and 2 demonstrate the technique of secure pump anchoring with a rectus fascial flap. Cases 3 and 4 show a technique to achieve reliable vascularized wound closure, and case 5 describes a technique to solve an uncommon problem of a thick subcutaneous abdominal tissue preventing the refill of the ITDP medication. CONCLUSION: Soft tissue flaps may serve as a treatment option for patients with uncommon ITDP complications. De-epithelialized dermal fasciocutaneous or fascial flaps may be developed to anchor the pump more securely. Cross-discipline collaboration may further delineate the technique, benefits, and outcomes of this approach.

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“…In the "year" column it can be seen when the paper was published, and in the "number of patients" the amount of people that took participation in the research. In general, the "follow-up" period [14]; [33][34][35][36][37][38][39][40][41]. NS = not specified.…”

Section: Infusion Pumps In Spasticitymentioning

confidence: 99%

Neurosurgical Spasticity Treatment: From Lesion to Neuromodulation Procedures

Carrillo-Ruíz¹,

Beltrán²,

Carrillo-Márquez³

et al. 2021

Frontiers in Clinical Neurosurgery

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Spasticity is one of the most important and residual signs after pyramidal and para-pyramidal catastrophic lesions after diverse neurological insults, including stroke, brain and spine trauma and post-radiation; infection and immunological diseases affecting nervous system, between others. Spasticity is normally a compensatory motor mechanism that could ameliorate the patients´ disability. Nevertheless, disastrous spasticity is described when the extremities force is diminished in the affected limbs, or when is impossible to wake o to take objects, maximum when hand or foot deformity is exposed. The objective of this chapter is centered in the neurosurgical treatment of spasticity, including brain lesions with specific targets and the spine with its different modalities. This review shows not only the basic aspects in these techniques, but also the option of infusion pumps and deep brain stimulation. To close, a proposal is stablished to determinate the possible path to treat the spasticity in the future.

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Intrathecal Baclofen Infusion Pumps in the Treatment of Spasticity: A Retrospective Cohort Study in a Portuguese Centre

Cited by 17 publications

References 27 publications

Treatment on patients with spastic cerebral palsy in the past 30 years: A systematic review and bibliometric analysis

Treatment on patients with spastic cerebral palsy in the past 30 years: A systematic review and bibliometric analysis

Treatment of Intrathecal Drug Pump Flipping Using Fascial Flaps: A Technical Description and Case Series

Neurosurgical Spasticity Treatment: From Lesion to Neuromodulation Procedures

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