Intrathecal 1% 2-chloroprocaine vs. 0.5% bupivacaine in ambulatory surgery: a prospective, observer-blinded, randomised, controlled trial

Abstract

Spinal anaesthesia with 50 mg of plain 1% 2-chloroprocaine is similar to 10 mg of plain 0.5% bupivacaine in terms of onset of sensory block at T10 but shows quicker recovery from anaesthesia than with 0.5% bupivacaine.

Comparison of 2-Chloroprocaine, Bupivacaine, and Lidocaine for Spinal Anesthesia in Patients Undergoing Knee Arthroscopy in an Outpatient Setting

“…This observation is confirmed by the findings of Lacasse et al 28 and Camponovo et al 26 The higher consumption of opioids did not affect patient satisfaction scores or the need for antiemetic medication for the treatment of PONV after opioids had been given.…”

The Addition of Epinephrine to Proxymetacaine or Oxybuprocaine Solution Increases the Depth and Duration of Cutaneous Analgesia in Rats

“…24,25 In the present experiment, the duration of action produced by proxymetacaine or oxybuprocaine was greater than that elicited by lidocaine as an infiltrative anesthetic. In agreement with the previous animal experiment, the duration of oxybuprocaine was comparable to that of bupivacaine in spinal anesthesia.…”

Randomised controlled trial of spinal anaesthesia with bupivacaine or 2‐chloroprocaine during caesarean section

“…5,27 The supplementation with colloids and phenylephrine could not always prevent hypotension, though the duration of hypotension was always less than 5 min. 5,27 The supplementation with colloids and phenylephrine could not always prevent hypotension, though the duration of hypotension was always less than 5 min.…”

“…It is safe to the parturient and newborn compared to general anaesthesia and has reportedly low maternal mortality. [4][5][6] Even with small doses of bupivacaine, disadvantages have been reported. The spinal component provides rapid onset of anaesthesia while the epidural catheter allows administration of local anaesthetics during and after surgery to maintain analgesia.…”