Intraspinal, Extradural Ependymoma

Seigel, Robert; Williams, Arvis G.; Mettler, Fred A.; Wicks, Jeffrey D.

doi:10.1097/00004728-198202000-00037

Cited by 9 publications

(2 citation statements)

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“…The exact reason for this difference in extent of resection is unclear, although complicated involvement of multiple nerve roots with potential for local invasion into surrounding structures, including extradural compartments and the sacrum, may contribute to difficulties in obtaining GTR for myxopapillary ependymomas in advanced stages. 6,9,62,65,77,[80][81][82] Furthermore, while classic ependymomas of the spinal cord may be encapsulated with well-delineated borders making then amenable to microsurgical en bloc GTR, myxopapillary ependymomas of the cauda equina or filum terminale may be intimately associated with neural structures, requiring piecemeal resection and making complete microsurgical GTR more difficult. One study, for example, has shown that encapsulated myxopapillary ependymomas removed en bloc had a recurrence rate of 10%, while those removed either piecemeal or subtotally had a recurrence rate of 19%.…”

Section: Discussionmentioning

confidence: 99%

Prognosis by tumor location in adults with spinal ependymomas

Oh¹,

Kim²,

Kaur³

et al. 2013

SPI

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Spinal ependymomas along different regions of spinal axis have different characteristics and clinical behaviors. Tumor grade, extent of resection, and PFS varied by tumor location (upper vs lower spinal regions), while OS did not. Recurrence rates were higher for the lower spinal cord tumors, despite a greater prevalence of lower WHO grade lesions, compared with upper spinal cord tumors, suggesting that tumor location along the spinal axis is an important prognostic factor.

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Section: Discussionmentioning

confidence: 99%

Prognosis by tumor location in adults with spinal ependymomas

Oh¹,

Kim²,

Kaur³

et al. 2013

SPI

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“…8 Only six cases have been reported in the English-language literature in which the tumor was thought to have arisen from within the sacrum, because there was minimal extension into the presacral space or regions dorsal to the sacrum. 10,[13][14][15]18,19 We report the only intraspinal extradural myxopapillary ependymoma known conclusively to arise from the filum terminale externa. …”

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confidence: 99%

Intraspinal extradural myxopapillary ependymoma of the sacrum arising from the filum terminale externa

Fourney¹,

Fuller²,

Gokaslan³

2000

Journal of Neurosurgery: Spine

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✓ Extradural ependymomas of the sacrococcygeal region are very rare, with most arising from the soft tissues of the presacral area or from the regions dorsal to the sacrum. In even rarer circumstances, the tumor may arise within the sacral canal, likely as a result of ependymal cells of the extradural filum terminale. Because of bone erosion caused by extension of the tumor into the pelvis or dorsal to the sacrum, a truly intraspinal extradural ependymoma in this region has until now never been clearly demonstrated. The authors present a patient with a myxopapillary ependymoma arising from the filum terminale externa in which there was no involvement of the intradural filum or extension outside the sacral canal. A review of the literature is presented, with emphasis on the pathogenesis and clinical management of these rare tumors.

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The Spine

Antoun¹

1990

Clinical Medicine and the Nervous System

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Intraspinal, Extradural Ependymoma

Cited by 9 publications

References 0 publications

Prognosis by tumor location in adults with spinal ependymomas

Prognosis by tumor location in adults with spinal ependymomas

Intraspinal extradural myxopapillary ependymoma of the sacrum arising from the filum terminale externa

The Spine

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