Intrascrotal lipoblastoma in adulthood

Abstract

This case report describes the case of a 37-year-old man that noticed an intrascrotal right mass with 1 month of evolution. During physical exam presented with a large mass at the inferior portion of the right testicle, clearly separated from the testicle, with a tender consistency and mobile. An ultrasound was performed that showed a solid and subcutaneous nodular lesion, extra testicular, heterogeneous, measuring 7.2 cm. Pelvic magnetic resonance imageMRI showed a lesion compatible with a lipoma. The patient was subjected to surgical excision of the lesion by scrotal access, having histology revealed a lipoblastoma (LB) of the scrotum. Histological diagnosis was obtained by microscopic characteristics (well-circumscribed fatty neoplasm) and immunohistochemistry (stains for CD34, S100 protein and PLAG1 were positive; stains for MDM2 and CDK4 were negative). LB is extremely rare after adolescence in any location, being this first described case of intrascrotal LB described in adulthood.

Scrotal Lipoblastoma with Radiological and Histological Correlation

“…Intrascrotal lipoblastomas are extremely rare, with fewer than 20 ever reported. 1 3 4 5 They usually present as a painless, growing scrotal mass within the first year of life. 1 2 Although benign, they can demonstrate locally invasive features or mass effect on adjacent structures.…”

“… 2 Lipoblastomas occurring in the scrotum are very rare, with only 18 cases being reported in the literature to date. 1 3 4 5 Treatment in all previous cases of intrascrotal lipoblastoma has been tumor excision with or without orchiectomy. 1 3 4 5 If the diagnosis is certain before surgery, a less invasive scrotal approach can be used, as reported in two cases previously, rather than an inguinal approach.…”

“… 1 3 4 5 Treatment in all previous cases of intrascrotal lipoblastoma has been tumor excision with or without orchiectomy. 1 3 4 5 If the diagnosis is certain before surgery, a less invasive scrotal approach can be used, as reported in two cases previously, rather than an inguinal approach. 3 4 There have been no reported cases of metastasis.…”

“… 1 3 4 5 If the diagnosis is certain before surgery, a less invasive scrotal approach can be used, as reported in two cases previously, rather than an inguinal approach. 3 4 There have been no reported cases of metastasis.…”

Retroperitoneal Lipoblastoma With Cord Compression in an Adult Patient: A Case Report

“…Another report mentioned similar cases in adults who underwent surgical resection as the main treatment [ 3 - 7 ]. A third study was of lipoblastoma in an adult reported as a scrotal mass treated by surgical resection [ 8 ]. Our case is unique because of the adult age and the presentation with cord compression.…”