1930
DOI: 10.1016/s0140-6736(00)86498-3
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Intrasacral Epidural Injection in the Treatment of Sciatica.

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Cited by 140 publications
(47 citation statements)
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“…It is unreasonable, however, to suspect any therapeutic action from extradural injection of 2 ml normal saline. Certainly Evans (1930) found that extradural injection of 30 nil of normal saline relieves sciatic pain, but this is fifteen times the amount used in o u r study. More likely the general improvement of our patients in both groups is at least in part due to the strict bed rest which was instituted directly after admission.…”
Section: Discussionmentioning
confidence: 92%
“…It is unreasonable, however, to suspect any therapeutic action from extradural injection of 2 ml normal saline. Certainly Evans (1930) found that extradural injection of 30 nil of normal saline relieves sciatic pain, but this is fifteen times the amount used in o u r study. More likely the general improvement of our patients in both groups is at least in part due to the strict bed rest which was instituted directly after admission.…”
Section: Discussionmentioning
confidence: 92%
“…Before the advent of corticosteroids there was a tendency to use large volumes of fluid (up to 200 ml), and Evans (1930) reported that the factor determining success was not the composition of the fluid injected but its volume, which he felt should exceed 60 ml. The putative mechanism was a "fluid dissection" of the extradural space, freeing the nerve root from the extruded disc material, or breaking down peridural adhesions.…”
Section: Methodsmentioning
confidence: 99%
“…La inyección de corticosteroides en el espacio epidural para el tratamiento del dolor crónico data de 1930; fue descrita en un artículo de Evans (27), tal como se le aplicó a nuestro paciente en una dilución junto con un anestésico local. En 1983 White (28) observó que hasta un 25 % de las punciones eran por fuera del espacio epidural.…”
Section: Discussionunclassified