Intraretinal Hemorrhage Associated With Leishmaniasis

Abstract

Abstract. A 39-year-old man presented with sudden loss of visual acuity caused by two retinal hemorrhages with no choroidal neovascularization (confirmed by fluorescein angiography). The patient was hospitalized for malaise, progressive pancytopenia, hepatosplenomegaly, progressive anemia, and perianal inflammation. Positive serologies were obtained for toxoplasmosis (IgG) and Leishmania (1/160). A diagnosis of visceral leishmaniasis was made, and the patient was treated with pentavalent antimonials. Two months later, best-corrected visual acuity was 20/25, with no residual scotoma. Indirect ophthalmoscopy showed complete resolution of the hemorrhages. This patient was an otherwise healthy immunocompetent adult who presented frank visceral leishmaniasis and retinal hemorrhages as the only ocular or systemic hemorrhagic findings, with spontaneous resolution after improvement of platelet levels. This rare cause of macular hemorrhage should be considered in areas where Leishmania is endemic. [Ophthalmic Surg Lasers Imaging 2003;34:212-214.]

Recurrent Kala Azar with Recurrent Post-Kala-Azar Anterior Uveitis in an Immuno competent Child: A Case Report

“…Ocular complications of kala azar are rare. The published literature on ocular complication of Leshmineasis includes reports of retinal haemorrhage [3], interstitial keratitis [4], blepharoconjunctivitis [5], and destruction of intraocular tissue by the organisms [6]. Dechant et al [7] in 1980 reported 3 cases of post Kala azar uveitis occurring during the course of, or shortly after the conclusion of the systemic illness.…”

Neurological manifestations of human leishmaniasis

“…Uveitis can progress to secondary glaucoma (Dechant et al, 1980), a disease of retinal cells. Retinal hemorrhages have been observed on fundic examination; in some cases multiple lesions were reported (>10 lesions in each eye) (De Cock et al, 1982;Montero et al, 2003).…”

Neurological disease in human and canine leishmaniasis – clinical features and immunopathogenesis

“…As mentioned above, one of the most frequent presentations of ocular leishmaniasis in patients with VL is uveitis, which can progress to secondary glaucoma. In fact, intraretinal haemorrhage is an important sign associated with leishmaniasis . Zijlstra & El‐Hassan reported uveitis, conjunctivitis and blepharitis in Sudanese patients as post‐VL manifestations.…”