Intrapulmonary pressures in the newborn infant

Smith, Clement A.

doi:10.1016/s0022-3476(42)80189-4

Cited by 16 publications

(1 citation statement)

References 5 publications

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“…Dieselben Autoren fanden sogar bis zu 120 cm H 20 keine sicheren traum atischen Schäden. N ur vereinzelt werden Drucke von 30 cm H 20 als gefährlich angegeben [79]. Die Gründe für die widersprechenden W erte sind : erstens der ungenügend beachtete Zeitfaktor für die positive Druckphase, zweitens die Inter pretation von term inalen Bronchiolen als dilatierte «Alveolen» bei noch nicht ausgereiften Lungen und schließlich muß berücksichtigt werden, daß der experimentell erzeugte Druck zufolge der Ström ungs widerstände der Zuleitungen (Tubus, Bronchien) erheblich reduziert wird und also am Erfolgsorgan (Alveolen) bereits viel niedriger ist (10).…”

unclassified

über die Reanimation asphyktischer Neugeborener

Bretscher¹

1964

Gynecol Obstet Invest

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unclassified

über die Reanimation asphyktischer Neugeborener

Bretscher¹

1964

Gynecol Obstet Invest

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Rupture of an Angiomatous Malformation of the Pleura in a Newborn Infant

Weiß¹

1958

Arch Pediatr Adolesc Med

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Hemodynamic Observations During Birth of the Lamb

Harned¹,

Wolkoff²,

Pickrell³

et al. 1961

Am J Dis Child

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In the process of birth, very complex circulatory changes occur during the transition from fetal to neonatal states. Because of the rapidity of these important changes and the dangers involved in their study, observations of the human infant have been limited. Studies of some of the physiologic changes that occur at birth of the newborn lamb have been performed by Barcroft,1 Barron,2 Dawes,3-11 Born,12-15 and others.16-18 The findings of these workers have provided insight into the circulatory changes at birth of the human infant. In their investigations, sequential observations of the birth of the unanesthetized lamb have been few. It is the purpose of this paper to describe the sequential hemodynamic changes during the birth of the unanesthetized lamb delivered by hysterotomy when the lamb is subjected to controlled stimuli similar to those encountered during birth. Materials and MethodsExperiments were performed on 18 lambs from 13 ewes. The ewes were given spinal anesthesia, 2 cc. of tetracaine (Pontocaine) hydrochloride in¬ jected into the lumbar region, with the ewe stand¬ ing in her usual manner. As the anesthesia becomes effective, the ewe's lower extremities be¬ come immobile. The neck and abdomen were then prepared by clipping. The ewe was then placed in the supine position in a specially built cradle which encloses the animal except for the neck and lower extremities which are brought out through U-shaped slots. Through a small cannula introduced into the external jugular vein, the blood was treated with heparin sodium. A tracheostomy was done under local anesthesia (lidocaine hydrochloride 2%) and a soft rubber tracheostomy tube was introduced to guarantee control of respiration. The extremities were tied securely with rope. Hys¬ terotomy was performed through a lower abdomi¬ nal incision avoiding the larger mammary veins.The lamb was cautiously delivered, preferablyhead first ; and the head was immediately capped with a saline-filled rubber glove. The lamb was then removed from the mother's abdomen and placed on a separate wooden platform attached to a Mayo stand. A U-shaped wedge in the platform protects the cord from undesirable pressure. The lamb was placed on its right side on this plat¬ form with its abdomen bridging the wedge. The lax umbilical cord lies in this wedge immediately above the uterus. One per cent lidocaine hydro¬ chloride was sprayed directly on the cord inter¬ mittently throughout the experiment to minimize constriction due to incidental trauma.After the lamb was secured to the platform, simultaneous incisions were made in the left jugular region and the right femoral triangle. Catheters were introduced through the left external jugular vein and through the right femoral artery. In this manner, samples were obtained from the pul¬ monary artery, right ventricle, and right atrium by way of the external jugular vein, and from the aorta, left ventricle, and left atrium by way of the femoral arteo'. For several experiments, a cannula was introduced also into the right femoral vein and...

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Intrapulmonary pressures in the newborn infant

Cited by 16 publications

References 5 publications

über die Reanimation asphyktischer Neugeborener

über die Reanimation asphyktischer Neugeborener

Rupture of an Angiomatous Malformation of the Pleura in a Newborn Infant

Hemodynamic Observations During Birth of the Lamb

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