“…The literature search identified 657 potentially eligible studies, of which 24 were further evaluated in full text. A total of 18 studies 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 with 1230 patients (mean 68 patients per study) reporting on nonoverlapping patient populations were considered eligible ( Supplemental Material Section 2 ). The characteristics of the included studies and patients are summarized in Tables 1 and 2 .…”