“…This study was incomplete as it did not include a group of animals given sucrose throughout the suckling period, and thus we cannot decide if the effects of sucrose in each of the three periods would be additive. There is at least evidence to suggest that the concentration of sucrose in artificial feeds given to suckling rats is directly related to the subsequent caries scores (Steinman & Haley, 1958). It has been claimed that carbohydrates, acting during tooth development, vary in their ability to alter caries resistance (Steinman & Haley, 1957aO'Day & Haley, 1959), but the inadequacy of experimental data and the lack of satisfactory control studies and statistical treatment prevent us from grading the different carbohydrates studied by Steinman and his associates.…”