Intraperitoneal distribution of ultrasound contrast medium imaged with B-mode ultrasound and colour-stimulated acoustic emission imaging

Diagnosis of hepatic hydrothorax using contrast‐enhanced ultrasonography with intraperitoneal injection of Sonazoid

“…Moreover, movement of ascitic fluid into the pleural cavity was observed in real time. Ultrasonography contrast agent injected into the abdominal cavity reportedly spreads uniformly in approximately 8 min 14 . Enhancement of the pleural cavity was observed within 1 min after Sonazoid injection in four of five patients in this study because the injection point was near the right diaphragm.…”

“…Ultrasonography contrast agent is used mainly for intravascular signal enhancement, but can also be used for non‐vascular imaging of body cavities, such as the urinary bladder, 12 uterine cavity 13 or peritoneal cavity 14 . Sonazoid is a second‐generation microbubble agent for ultrasonography, comprising perfluorobutane microbubbles with a median diameter of 2–3 µm.…”

Endocavitary contrast‐enhanced ultrasound: A technique whose time has come?

“…Proposed indications for eCEUS include locating tubes and drains in body cavities, abscesses, or collections 13,14 ; estimating the dimensions and detecting the communications of fluid collections 13,[15][16][17] ; percutaneous, transpapillary, or intraoperative visualization of the biliary system [16][17][18][19][20][21][22][23] ; demonstrating thoracoabdominal communication in cases of suspected hepatic hydrothorax [24][25][26] ; detecting and quantifying fistulae in various locations [27][28][29] digestive tract after oral or colonic administration of USCMs 17,[30][31][32][33][34] ; confirming correct placement of a percutaneous nephrostomy 35 ; and evaluating obstructive disease of the salivary glands. 36 Endocavitary administration of USCMs has recently been included in guidelines from the European Federation of Societies for Ultrasound in Medicine and Biology, which emphasize that no well-established indications exist at present but recommend considering the use of eCEUS if alternatives (eg, fluoroscopy, need to transport critically ill patients) may carry a higher risk for the patient.…”