Intrapatient Comparison of 2-Deoxy-2-[F-18]fluoro-d-glucose with Positron EmissionTomography/Computed Tomography to Tc-99m Fanolesomab (NeutroSpec) for Localization of Infection

Klingensmith, William C.; Perlman, Daniel; Baum, Kenneth

doi:10.1007/s11307-007-0097-0

Cited by 9 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…99m Tc-fanolesumab is a murine anti-CD15 IgM monoclonal antibody labeled with 99m Tc which was approved for imaging of equivocal cases of acute appendicitis and was in trials for use in imaging osteomyelitis and occult infection (6,90,104,162 (90). Shortly after infusion, a transient drop in the absolute neutrophil number has been observed, but no infectious complications have been attributed to Tc-fanolesumab (102,104).…”

Section: Monoclonal Antibodies For Imagingmentioning

confidence: 99%

Infectious Complications Associated with Monoclonal Antibodies and Related Small Molecules

Salvaña

Salata

2009

Clin Microbiol Rev

View full text Add to dashboard Cite

SUMMARY Biologics are increasingly becoming part of routine disease management. As more agents are developed, the challenge of keeping track of indications and side effects is growing. While biologics represent a milestone in targeted and specific therapy, they are not without drawbacks, and the judicious use of these “magic bullets” is essential if their full potential is to be realized. Infectious complications in particular are not an uncommon side effect of therapy, whether as a direct consequence of the agent or because of the underlying disease process. With this in mind, we have reviewed and summarized the risks of infection and the infectious disease-related complications for all FDA-approved monoclonal antibodies and some related small molecules, and we discuss the probable mechanisms involved in immunosuppression as well as recommendations for prophylaxis and treatment of specific disease entities.

show abstract

Section: Monoclonal Antibodies For Imagingmentioning

confidence: 99%

Infectious Complications Associated with Monoclonal Antibodies and Related Small Molecules

Salvaña

Salata

2009

Clin Microbiol Rev

View full text Add to dashboard Cite

show abstract

“…The difference in the diffusion of water molecules among tissues enables DW-MRI to detect malignant tumors and differentiate them from benign masses ( 12 ). Previous studies have shown that DW-MRI is comparable with PET/CT in detecting malignant lesions ( 13 – 15 ). Numerous studies reported that DW-MRI provided more accurate delineation for a number of cancer types, including prostate, head and neck, and cranial tumors ( 16 – 18 ).…”

Section: Introductionmentioning

confidence: 97%

Implementation of diffusion-weighted magnetic resonance imaging in target delineation of central lung cancer accompanied with atelectasis in precision radiotherapy

Zhang

Gong

et al. 2017

Oncology Letters

View full text Add to dashboard Cite

Radiotherapy, particularly the target delineation of cancer based on scanned images, plays a key role in the planning of cancer treatment. Recently, diffusion-weighted magnetic resonance imaging (DW-MRI) has emerged as a prospective superior procedure compared with intensified computed tomography (CT) and positron emission tomography (PET) in the target delineation of cancer. However, the implication of DW-MRI in lung cancer, the leading cause of cancer-associated mortality worldwide, has not been extensively evaluated. In the present study, the gross target volumes of lung cancer masses delineated using the DW-MRI, CT and PET procedures were compared in a pairwise manner in a group of 27 lung cancer patients accompanied with atelectasis of various levels. The data showed that compared with CT and PET procedures, DW-MRI has a more precise delineation of lung cancer while exhibiting higher reproducibility. Together with the fact that it is non-invasive and cost-effective, these data demonstrate the great application potential of the DW-MRI procedure in cancer precision radiotherapy.

show abstract

Radiolabeled Antibodies for Diagnostic Imaging

Palestro

2014

Handbook of Therapeutic Antibodies

View full text Add to dashboard Cite

Intrapatient Comparison of 2-Deoxy-2-[F-18]fluoro-d-glucose with Positron EmissionTomography/Computed Tomography to Tc-99m Fanolesomab (NeutroSpec) for Localization of Infection

Abstract: FDG-PET/CT is superior to Tc-99m fanolesomab for detecting and localizing sites of infection.

Cited by 9 publications

References 10 publications

Infectious Complications Associated with Monoclonal Antibodies and Related Small Molecules

Infectious Complications Associated with Monoclonal Antibodies and Related Small Molecules

Implementation of diffusion-weighted magnetic resonance imaging in target delineation of central lung cancer accompanied with atelectasis in precision radiotherapy

Radiolabeled Antibodies for Diagnostic Imaging

Contact Info

Product

Resources

About