“…EA has been commonly reported in association with atrial septal defect (ASD) or PFO, right ventricular outflow tract obstruction, and WPW syndrome, as demonstrated in the present case [ 2 , 4 ]. To the best of our knowledge, this is the 5th case report of EA with PFO/ASD-associated septic paradoxical embolism, but the first case report in the setting of septic emboli originating from a lower extremity abscess [ 3 , [5] , [6] , [7] ].…”