Intraosseous Phlebography, Intraosseous Pressure Measurements and<sup>99m</sup>Tc-Polyphosphate Scintigraphy in Patients with Various Painful Conditions in the hip and Knee

Arnoldi, Carl C.; Djurhuus, J. C.; Heerfordt, J; Karle, A

doi:10.3109/17453678008990764

Cited by 88 publications

(44 citation statements)

References 13 publications

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“…The coincidence of OA, rest pain, and high intraosseous pressures have long been described (35,36) and treatment via fenestration or drainage has been attempted.…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

Synovial fluid pro-inflammatory profile differs according to the characteristics of knee pain

Leung

Huebner

Haaland

et al. 2017

Osteoarthritis and Cartilage

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“…The coincidence of OA, rest pain, and high intraosseous pressures have long been described (35,36) and treatment via fenestration or drainage has been attempted.…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

Synovial fluid pro-inflammatory profile differs according to the characteristics of knee pain

Leung

Huebner

Haaland

et al. 2017

Osteoarthritis and Cartilage

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“…15 Arnoldi et al reported that patients with knee and hip OA often have poor venous drainage from the marrow with subsequent intraosseous hypertension. 1 This increased pressure in a closed compartment interferes with the blood circulation with resultant osseous ischemia. This hypothesis is in agreement with an histopathologic examination in osteoarthritic knees with BME.…”

Section: Discussionmentioning

confidence: 99%

Influence of High Tibial Osteotomy on Bone Marrow Edema in the Knee

Kröner¹,

Berger²,

Kluger³

et al. 2007

Clinical Orthopaedics and Related Research

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To determine the influence of high tibial osteotomy on subchondral bone marrow edema in medial osteoarthritis of the varus knee, full leg-length radiographs and magnetic resonance imaging were performed in 20 patients (20 knees) before surgery, 1 year postoperatively, and at a mean of 7 years postoperatively. The extent of bone marrow edema in the medial compartment was quantified with magnetic resonance imaging in two planes using the formula for a prolate ellipsoid as follows: length x width x depth x pi/6. We used the Japanese Orthopaedic Association knee score for clinical evaluation. At the last followup, all knees with valgus alignment (10/10) showed reduced edema. In contrast, bone marrow edema increased or remained unchanged in four of 10 knees with neutral or varus alignment. The percentage of satisfactory results was 100% (10/10) in valgus knees and only 30% (3/10) in neutral or varus knees. Extent of bone marrow edema at the followup correlated with the mechanical axis and knee score. Because of the prognostic value of bone marrow abnormalities in the medial compartment observed on magnetic resonance imaging, early lateral closing wedge osteotomy should be considered in patients with varus malalignment and bone marrow edema even in mild cases of medial osteoarthritis.

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“…Pioneering work on the association between bone pathologies and pain was undertaken by Arnoldi et al 27 28 in the 1970s and 1980s using intraosseous pressure measurement and other techniques. In the 1990s, bone scintigraphy was used to determine whether subchondral bone activity was related to both pain and progression of OA,29–31 providing an impetus to bone research in OA.…”

Section: Discussionmentioning

confidence: 99%

Association of bone attrition with knee pain, stiffness and disability: a cross-sectional study

Reichenbach

Dieppe

Nüesch

et al. 2010

Annals of the Rheumatic Diseases

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Intraosseous Phlebography, Intraosseous Pressure Measurements and^99mTc-Polyphosphate Scintigraphy in Patients with Various Painful Conditions in the hip and Knee

Cited by 88 publications

References 13 publications

Synovial fluid pro-inflammatory profile differs according to the characteristics of knee pain

Synovial fluid pro-inflammatory profile differs according to the characteristics of knee pain

Influence of High Tibial Osteotomy on Bone Marrow Edema in the Knee

Association of bone attrition with knee pain, stiffness and disability: a cross-sectional study

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Intraosseous Phlebography, Intraosseous Pressure Measurements and99mTc-Polyphosphate Scintigraphy in Patients with Various Painful Conditions in the hip and Knee

Cited by 88 publications

References 13 publications

Synovial fluid pro-inflammatory profile differs according to the characteristics of knee pain

Synovial fluid pro-inflammatory profile differs according to the characteristics of knee pain

Influence of High Tibial Osteotomy on Bone Marrow Edema in the Knee

Association of bone attrition with knee pain, stiffness and disability: a cross-sectional study

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Intraosseous Phlebography, Intraosseous Pressure Measurements and^99mTc-Polyphosphate Scintigraphy in Patients with Various Painful Conditions in the hip and Knee