Intraosseous Meningioma Masquerading as Fibrous Dysplasia

Shaftel, Solomon S.; Alameddine, Raafat; Oh, Sang Rog; Korn, Bobby S.; Lin, Jonathan H.; Kikkawa, Don O.

doi:10.4172/2476-2024.1000104

Cited by 3 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Intraosseous sphenoid wing meningioma can closely mimic FD both clinically and radiologically 10. The microscopy at a low magnification closely mimics a meningioma and is easy to misdiagnose; however, the characteristic features of meningioma—such as a whorling pattern, a syncytial arrangement, and bland nuclear features—are typically absent.…”

Section: Discussionmentioning

confidence: 97%

“…The microscopy at a low magnification closely mimics a meningioma and is easy to misdiagnose; however, the characteristic features of meningioma—such as a whorling pattern, a syncytial arrangement, and bland nuclear features—are typically absent. The key morphological features of FD include trabeculae of immature woven bone without osteoblastic rimming, which sometimes closely mimics whorls and psammoma bodies of meningioma 10…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Monostotic craniofacial fibrous dysplasia: report of two cases with interesting histology

Singh¹,

Gupta²,

Salunke³

2019

Autops. Case Rep.

View full text Add to dashboard Cite

Fibrous dysplasia (FD) is a relatively rare osseous disease of unknown etiology, wherein the normal bone is replaced by collagen-rich tissue, comprising of fibroblasts and variably abundant immature woven bone. Clinically, it may involve a single bone or multiple bones. It commonly arises in the jaw bone, skull, rib, and proximal femur. Those arising in the skull and the jaw are together termed “craniofacial fibrous dysplasia.” The differential diagnosis at this location includes meningioma and metastatic carcinoma. In this report, we highlight two diagnostically challenging cases presenting with orbital swelling and headache as the main complaints. Our first case was misinterpreted as meningioma on intraoperative squash smear, and paraffin sections revealed characteristic features of FD. The second case highlights the morphological feature of non-specific cystic degeneration occurring in FD. Radiographs in such cases show cystic swelling, which is indicative of a secondary aneurysmal bone cyst.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Monostotic craniofacial fibrous dysplasia: report of two cases with interesting histology

Singh¹,

Gupta²,

Salunke³

2019

Autops. Case Rep.

View full text Add to dashboard Cite

show abstract

“…This is due to the failure of early diagnosis, inadequate resection because of the involvement of the neurovascular structure, and also fear of the surgeons into iatrogenic death and severe complication in radical resection [6]. Furthermore, some require orbital reconstruction [6], and others will proceed with radiation therapy [11].…”

Section: Discussionmentioning

confidence: 99%

Meningioma Mimicking Fibrous Dysplasia

Kamaluddin

Samsudin

Hitam

et al. 2019

Cureus

View full text Add to dashboard Cite

Despite being among the common primary intracranial tumors, intraosseous craniofacial meningioma is the least common subtype of meningioma accounting for only 1-2% of intracranial meningiomas. Interestingly, it can display clinical and radiologic features that can be confused for fibrous dysplasia. Scan imaging and biopsy are crucial for the diagnosis as well as for further proper treatment. We report a case of unilateral eye proptosis and optic neuropathy which was initially thought for fibrous dysplasia. Later the histopathology revealed meningioma grade 1. As the clinical presentations are almost undifferentiated, diagnosis and further prompt treatment are challenging.

show abstract

“…The sphenoidal involvement has been anecdotally reported in this condition, but the fact that other sinuses are usually spared, the rare and scarce cyst-like changes and the occurrence after the fifth decade are all useful features for differentiation from fibrous dysplasia [ 40 ]. Intraosseous meningioma — compared with fibrous dysplasia — shows feathering of lesions edges, soft tissue involvement and vivid homogenous CE [ 41 ]. Ossifying fibroma is a benign tumour with similar features, but it typically shows better-defined boundaries with osteosclerotic shells, whereas the periphery of fibrous dysplasia usually blends with the surrounding bone [ 42 ].…”

Section: Developmental Lesions (Table 1 )mentioning

confidence: 99%

A practical overview of CT and MRI features of developmental, inflammatory, and neoplastic lesions of the sphenoid body and clivus

et al. 2022

View full text Add to dashboard Cite

The sphenoid bone is an unpaired bone that contributes to the formation of the skull base. Despite the enormous progress in transnasal endoscopic visualisation, imaging techniques remain the cornerstones to characterise any pathological condition arising in this area. In the present review, we offer a bird’s-eye view of the developmental, inflammatory, and neoplastic alterations affecting the sphenoid body and clivus, with the aim to propose a practical diagnostic aid for radiologists based on clinico-epidemiological, computed tomography, and magnetic resonance imaging features.

show abstract

Intraosseous Meningioma Masquerading as Fibrous Dysplasia

Abstract: Background: Intraosseous meningiomas often display clinical and radiologic features that can be confused for fibrous dysplasia. Histopathology usually confirms the diagnosis. We present a case initially misdiagnosed as fibrous dysplasia by histopathology.

Cited by 3 publications

References 8 publications

Monostotic craniofacial fibrous dysplasia: report of two cases with interesting histology

Monostotic craniofacial fibrous dysplasia: report of two cases with interesting histology

Meningioma Mimicking Fibrous Dysplasia

A practical overview of CT and MRI features of developmental, inflammatory, and neoplastic lesions of the sphenoid body and clivus

Contact Info

Product

Resources

About