Intraosseous lipomatosis. A case report

Szabó, Miklós; Karlinger, Kinga; Gonda, A

doi:10.1302/0301-620x.73b1.1991740

Cited by 11 publications

(4 citation statements)

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“…5,6 These lesions can progress to pathological fractures. 9 In our three patients, both the upper and lower limb involvement was seen and there was no coexisting condition that could have predisposed to those lesions. Only one lesion accepted as healed insidious compression fracture in our three cases.…”

Section: Discussionmentioning

confidence: 57%

Multiple Intraosseous Lipoma: Report of Three Cases

Kalender¹,

Özkan²,

Sayar³

et al. 2011

UHOD

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Multiple intraosseous lipoma (MIOL) is extremely rare bone tumour. Its real incidence is estimated as much more because of most of these tumours is asymptomatic and undiagnosed. We reported 3 MIOL patients involving both upper and lower extremity. Two female patient with 30 and 26 age and one male with 52 years old represented by intraosseous lipomatous lesions involving bilateral wrist and hand bones, distal radius, proximal and distal femur, patella, proximal and distal tibia metaphyses, distal fibula, ankle and foot bones. Painful lesions were curetted and grafted by allograft. A distal radius fracture is treated by closed reduction and percutaneus pining. All the lesions healed that is managed by surgery. The asymptomatic lesions were not treated anyway. MIOL needs surgery in the case of pain, pathologic fracture, pathologic diagnosis confirmation and impending fracture. The malign transformation potential is present even rare. It must be followed in long period and carefully. CT is a good diagnostic imaging allowing negative density measurement in lesions between -60 and -110 HU. Keywords: Intraosseous lipomatosis ÖZET Multipl ‹ntraosseoz Lipoma: Üç Olgu SunumuMultipl intraosseoz lipoma (M‹OL) kemik tümörleri içinde çok nadir bir tümördür. Ancak gerçek insidans› asemptomatik oldu¤u ve tan› konulmadan kald›¤› için daha yüksek oldu¤u tahmin edilmektedir. Bu tümörün multipl kemik tutulumu literatürde çok nadir olarak bildirilmifltir. Biz hem üst hem alt ekstremiteyi ilgilendiren 3 vaka sunduk. Otuz ve 26 yafl›nda 2 kad›n ve 52 yafl›nda erkek hastada her iki el bilek, distal radius, falankslar, karpal ve metakarpal kemikler, femur proksimal, femur distal metafizleri, patella, proksimal ve distal tibia metafizleri, fibula distali, ayak bile¤i ve ayak kemiklerinin tümünü tutuldu¤u multip›l intraosseoz lipoma vakas› sunuldu. Vakalarda a¤r› yapan lezyonlar küretaj ve allogreft greftleme ile tedavi edildi. Radius distalinde k›r›k geliflen bir hastada kapal› redük-siyon perkutan pinleme uyguland›. Müdahale edilen bütün lezyonlarda düzelme izlendi. Semptom vermeyen lezyonlara tedavi uygulanmad›. M‹OL lezyonlar› klasik intraosseoz lipomlar gibi yaln›zca semptom veren lezyonlarda, k›r›k tehdidi olan durumlarda veya tan› amaçl› cerrahi müdahaleye ihtiyaç duyarlar. Çok nadir de olsa malignite geliflim riski mevcuttur. Hastalar›n uzun sureli takibi gerekir. Bilgisayarl› tomografi (BT) ile lezyon içi densite ölçümünde negatif de¤er

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Section: Discussionmentioning

confidence: 57%

Multiple Intraosseous Lipoma: Report of Three Cases

Kalender¹,

Özkan²,

Sayar³

et al. 2011

UHOD

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“…Although the etiology is unknown, multiple intraosseous lipomas have been reported in the patients with hyperlipoproteinemia, macrodystrophia lipomatosa and as a congenital variant following autosomal pattern of inheritance [1,2,6]. These lesions can progress to pathological fractures [3]. In our patient, both the upper and lower limb involvement was seen and there was no coexisting condition that could have predisposed to this condition.…”

Section: Discussionmentioning

confidence: 63%

“…The management involves curette and graft of the symptomatic and progressive lesions [3,12]. Follow up can be helpful as these often progress to pathological fractures.…”

Section: Discussionmentioning

confidence: 99%

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Multiple intraosseous lipomatosis: a case report

Rehani

Wissman

2009

Cases Journal

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IntroductionIntraosseous lipoma is an uncommon entity that presents almost exclusively as a solitary lesion. Multiple intraosseous lipomas are exceedingly rare with only a few cases being reported in the literature.Case presentationWe present a case of 43-year-old African American female who presented with left leg and left wrist pain. The initial radiographs revealed well-defined radiolucent lesions in multiple bones involving the left wrist and the left lower limb. The magnetic resonance demonstrated multiple lesions, which showed high signal on the T1 and low signal on the fat suppressed T2 images. This favored the diagnosis of intraosseous lipomatosis that was confirmed by biopsy.ConclusionMultiple intraosseous lipomatosis is an uncommon but important differential for multiple radiolucent lesions on the plain radiographs. This condition can lead to pathological fractures. Magnetic resonance imaging can aid in providing an accurate diagnosis. The awareness of this condition can help the clinician in guiding the correct diagnosis and management.

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Intraosseous lipoma: report of 35 new cases and a review of the literature

et al. 2003

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Although there is correlation between the histological and radiological features of intraosseous lipomas in general, some discrepancies occur in the radiological appearances of lipomas in different sites. The evidence that these lesions are true benign tumours of fat is controversial. Several aetiological factors have been implicated in their development. The constant location of os calcis lesions at the critical angle suggests an aetiology that may be related to biomechanical lines of stress. In other instances it is possible that involution of pre-existing lesions may lead to the development of lipomas.

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Intraosseous lipomatosis. A case report

Cited by 11 publications

References 0 publications

Multiple Intraosseous Lipoma: Report of Three Cases

Multiple Intraosseous Lipoma: Report of Three Cases

Multiple intraosseous lipomatosis: a case report

Intraosseous lipoma: report of 35 new cases and a review of the literature

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