Intraosseous Lipoma: 18 Years of Experience at a Single Institution

Abstract

BackgroundIntraosseous lipoma is a very rare lesion that constitutes no more than 0.1% of all bone tumors. We analyzed 21 cases of intraosseous lipoma at a single institution for clinical and radiographic characteristics.MethodsA retrospective study was performed on 21 pathologically confirmed intraosseous lipomas treated in our hospital from 2000 to 2017. Simple X-ray and magnetic resonance imaging findings and medical records were reviewed. Patients' age, sex, and clinical symptoms were investigated. From the radiographic images, the site of the lesion, calcification, bony expansion, and stage of the lesion were evaluated. Correlations between the degree of involution and clinical symptoms were analyzed.ResultsThe mean age of patients was 50 years (range, 20 to 67 years), and there were 13 males and eight females. The mean lesion size was 6.1 cm (range, 2.5 to 13.6 cm). The most common anatomical site of the lesion was the femur (seven cases), and three cases occurred in flat bones such as the ilium and scapula. Visual analogue scale score for pain was 3 to 6 in 15 patients. There were no complaints of functional limitation. There was no correlation between the degree of degeneration and clinical symptoms (p = 1.000). Curettage was performed as a surgical treatment in 20 patients, and bone graft was performed using a bone chip. Excision was performed in one patient. Pain was resolved in seven of 11 patients with a complaint of preoperative pain; intermittent pain remained in four cases. There was no local recurrence or malignant change during the follow-up.ConclusionsThere was no correlation between the degree of degeneration and clinical symptoms. Pain was the most common clinical symptom, but it was rarely accompanied by functional limitation. However, it is important to distinguish it from other pain-inducing disorders. The incidence of intraosseous lipomas is low, and detection based on various imaging findings can be difficult. Clear understanding of the radiographic findings and symptoms of intraosseous lipoma is helpful for diagnosis and differentiation.

A rare case of intraosseous lipoma of distal tibia – A case report and review of literature

“…Intraosseous lipoma is a considered as a rare benign bone lesion accounting for <0.1 % of all primary bone tumors [1][2][3] . Although, it can occur at any age, the highest incidence is reported to be in 4 th , 5 th and 6 th decades of life 3 . Males are more frequently affected than the females 1,3-6 but some reports showed no sex predilection 3 .…”

“…Intraosseous lipoma is a very rare neoplasm accounting for < 0.1 % of primary bone tumors [1][2][3] . Pain is the leading symptoms in majority of the reported cases [3][4][5] . However, 30% of the cases are known to be asymptomatic and are detected incidentally while investigating for other unrelated reasons 3 .…”

“…Pain is the leading symptoms in majority of the reported cases [3][4][5] . However, 30% of the cases are known to be asymptomatic and are detected incidentally while investigating for other unrelated reasons 3 . It has no gender or ethnic predilection but some reports found slight male predominance 1,[3][4][5][6] .…”

“…However, 30% of the cases are known to be asymptomatic and are detected incidentally while investigating for other unrelated reasons 3 . It has no gender or ethnic predilection but some reports found slight male predominance 1,[3][4][5][6] . It frequently occurs in lower limb 4 , particularly in os calcis, femur and fibula in decreasing order 4,7 .…”

Radiological diagnostics of rare benign bone tumor intraosseous lipoma: Intraosseous lipoma

“…Asymptomatic intraosseous lipoma of the calcaneus can undergo spontaneous involution; therefore, their treatment is conservative. The surgical removal is suggested in case of severe pain and as prevention of a pathologic fracture, especially when the lesion is in weight-bearing bone 3,5,10,11 . The surgical curettage with or without grafting is a method of choice.…”